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CBL2 (Tyr700) Antibody, Biotin Conjugated

CBL2 (Tyr700) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, CBL2 (Tyr700) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenCBL2 Tyr700
SpecificityThis is a highly specific antibody against CBL2 Tyr700
ModificationPhosphorylation
Modification siteTyr700
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human C CBL around the phosphorylation site of Tyr700
Gene ID number867
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background As such it functions as a negative regulator of many signal transduction pathways, Mar 2012], Mutations in this gene are also the cause of Noonan syndrome-like disorder, The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome, This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia, This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation, This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates, [provided by RefSeq, This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms RNF55 c-Cbl
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetCBL2 (Tyr700) Conjugated
Short name Conjugated, CBL2 (Tyr700) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, CBL2 (Tyr700) (Antibody to)
Alternative techniqueantibodies
Identity 1541
Gene CBL
Long gene name Cbl proto-oncogene
Synonyms gene CBL2
Synonyms gene name Cas-Br-M (murine) ecotropic retroviral transforming sequence Cbl proto-oncogene, E3 ubiquitin protein ligase
Synonyms name oncogene CBL2
Locus 11q23, 3
Discovery year 1989-06-30
GenBank acession X57110
Entrez gene record 867
Pubmed identfication 2013228
RefSeq identity NM_005188
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000166170
Locus Specific Databases LRG_608

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