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CBS Antibody

CBS Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCBS
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the CBS antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points
Intented useThis CBS antibodyis to be used only for research purposes and not for diagnostics
Gene ID #875
PurityAntigen affinity
Description CBS catalyzes the first step of the transsulfuration pathway, It is a multidomain enzyme composed of an N-terminal enzymatic domain and two CBS domains, It is mapped to 21q22, It uses the cofactor pyridoxal-phosphate (PLP) and can be allosterically regulated by effectors such as the ubiquitous cofactor S-adenosyl-L-methionine (adoMet), The gene is the most common locus for mutations associated with homocystinuria, This enzyme belongs to the family of lyases, from homocysteine to cystathionine, ranging in size from 42 to 299 bp, the hydro-lyases, to be specific, which cleave carbon-oxygen bonds, 3 and contains 23 exons, Cystathionine-beta-synthase is an enzyme that in humans is encoded by the CBS gene
ImmunogenHuman partial recombinant protein (AA 331-551) was used as the immunogen for this CBS antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CBS antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCBS
Short nameCBS Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCBS (Antibody to)
Alternative techniqueantibodies
Identity 1550
Gene CBS
Long gene name cystathionine-beta-synthase
Synonyms HIP4
Locus 21q22, 3
Discovery year 2001-06-22
GenBank acession L14577
Entrez gene record 875
Pubmed identfication 9790750
RefSeq identity NM_000071
Havana BLAST/BLAT OTTHUMG00000086834
Locus Specific Databases Cystathionine beta-synthase database LRG_777

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