Name : CCDC98 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN4138305109
| Long name | CCDC98 Primary Polyclonal Antibody |
| Also known as | CCDC98 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CCDC98 |
| Specificity | This is a highly specific antibody against CCDC98 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 85-135/409 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CCDC98 |
| Gene ID number | 84142 |
| Swiss Prot | Q6UWZ7 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Component of the BRCA1-A complex, The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs, Involved in DNA damage response and double-strand break (DSB) repair |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | BRCA1-A complex subunit Abraxas, CCDC98, Coiled-coil domain-containing protein 98, FAM175A, Protein FAM175A, UNQ496/PRO1013, ABRA1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CCDC98 |
| Short name | CCDC98 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CCDC98 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 25829 |
| Gene | FAM175A |
| Long gene name | family with sequence similarity 175 member A |
| Synonyms gene | CCDC98 |
| Synonyms gene name | coiled-coil domain containing 98 family with sequence similarity 175, member A |
| Synonyms | FLJ13614 ABRA1 ABRAXAS |
| Synonyms name | Abraxas protein |
| Locus | 4q21, 23 |
| Discovery year | 2006-04-03 |
| GenBank acession | AK023676 |
| Entrez gene record | 84142 |
| Pubmed identfication | 12975309 17525340 |
| RefSeq identity | NM_139076 |
| Classification | BRCA1 A complex |
| Havana BLAST/BLAT | OTTHUMG00000130429 |