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CCR5 Antibody

CCR5 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCCR5
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the CCR5 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis CCR5 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P51681
PurityAntigen affinity
Description Defective alleles of this gene have been associated with the HIV infection resistance, Expression of this gene was also detected in a promyeloblastic cell line, The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), This gene is located at the chemokine receptor gene cluster region, This protein is expressed by T cells and macrophages, Two transcript variants encoding the same protein have been found for this gene, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES), suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation, to enter host cells, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors, This gene encodes a member of the beta chemokine receptor family
ImmunogenA portion of amino acids 151-177 from the human protein was used as the immunogen for this CCR5 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CCR5 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCCR5
Short nameCCR5 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namechemokine (C-C motif) receptor 5 (gene/pseudogene) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CC-CKR-5 and CCCKR5 and CCR-5 and CD195 and CKR-5 and CKR5 and CMKBR5 and IDDM22, CCR5 and IDBG-30229 and ENSG00000160791 and 1234, CCR5 and IDBG-646247 and ENSBTAG00000008099 and 497017, Cell surfaces, chemokine (C-C motif) ligand 5 binding, this GO :0000165 and MAPK cascade and biological process this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0003779 and actin binding and molecular function this GO :0004435 and phosphatidylinositol phospholipase C activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005768 and endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006816 and calcium ion transport and biological process this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0006968 and cellular defense response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0014808 and release of sequestered calcium ion into cytosol by sarcoplasmic reticulum and biological process this GO :0015026 and coreceptor activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016493 and C-C chemokine receptor activity and molecular function this GO :0019722 and calcium-mediated signaling and biological process this GO :0019957 and C-C chemokine binding and molecular function this GO :0023052 and signaling and biological process this GO :0030260 and entry into host cell and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process this GO :0070723 and response to cholesterol and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071791 and chemokine (C-C motif) ligand 5 binding and molecular function, this GO :0003779: actin binding, this GO :0003779: actin binding and also this GO :0004435: phosphatidylinositol phospholipase C activity and also this GO :0004930: G-protein coupled receptor activity and also this GO :0004950: chemokine receptor activity and also this GO :0005515: protein binding and also this GO :0015026: coreceptor activity and also this GO :0016493: C-C chemokine receptor activity and also this GO :0019957: C-C chemokine binding and also this GO :0071791: chemokine (C-C motif) ligand 5 binding, this GO :0004435: phosphatidylinositol phospholipase C activity, this GO :0004930: G-protein coupled receptor activity, this GO :0004950: chemokine receptor activity, this GO :0005515: protein binding, this GO :0015026: coreceptor activity, this GO :0016493: C-C chemokine receptor activity, this GO :0019957: C-C chemokine binding, this GO :0071791: chemokine (C-C motif) ligand 5 binding, chemokine (C-C motif) receptor 5 (gene/pseudogene)
Identity 1606
Gene CCR5
Long gene name C-C motif chemokine receptor 5 (gene/pseudogene)
Synonyms gene CMKBR5
Synonyms gene name chemokine (C-C motif) receptor 5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
Synonyms CKR-5 CC-CKR-5 CKR5 CD195 IDDM22
Locus 3p21, 31
Discovery year 1996-05-15
Entrez gene record 1234
Pubmed identfication 8639485
RefSeq identity NM_000579
Classification CD molecules C-C motif chemokine receptors
Havana BLAST/BLAT OTTHUMG00000133481

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