Name : CD109 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6342984445
| Long name | CD109 Primary Polyclonal Antibody |
| Also known as | CD109 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CD109 |
| Specificity | This is a highly specific antibody against CD109 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 920-970/1145 |
| Subcellular location | Cell membrane |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD109 |
| Gene ID number | 135228 |
| Swiss Prot | Q6YHK3 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Although it has been suggested that T-cell CD109 may play a role in antibody-inducing T-helper function and it is known that platelet CD109 carries the Gov alloantigen system, It is a glycosylphosphatidylinositol (GPI)-linked cell surface glycoprotein of approximately 170 kd found onendothelial cells, activated platelets and T-cells and on a subset of hematopoietic stem and progenitor cells, the role of CD109 in hematopoietic cells remains largely unknown, CD109 has been identified as part of the TGF-beta receptor system in human keratinocytes and upregulation of CD109 expression has been observed in several different types of tumour, CD109 is a a novel member of the alpha2-macroglobulin (alpha2M)/complement superfamily |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 150 kDa TGF-beta-1-binding protein, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7, CD109, CD109 antigen, CPAMD7, Platelet-specific Gov antigen, r150, p180 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CD109 |
| Short name | CD109 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CD109 molecule (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | CD109 and IDBG-629598 and ENSBTAG00000013222 and 534043, CD109 and IDBG-92570 and ENSG00000156535 and 135228, Cd109 and IDBG-187096 and ENSMUSG00000046186 and 235505, Extracellular, this GO :0004866 and endopeptidase inhibitor activity and molecular function this GO :0004867 and serine-type endopeptidase inhibitor activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0031225 and anchored component of membrane and cellular component this GO :0050431 and transforming growth factor beta binding and molecular function this GO :0061045 and negative regulation of wound healing and biological process, this GO :0004866: endopeptidase inhibitor activity, this GO :0004866: endopeptidase inhibitor activity and also this GO :0004867: serine-type endopeptidase inhibitor activity and also this GO :0050431: transforming growth factor beta binding, this GO :0004867: serine-type endopeptidase inhibitor activity, this GO :0050431: transforming growth factor beta binding, transforming growth factor beta binding, CD109 molecule |
| Identity | 21685 |
| Gene | CD109 |
| Long gene name | CD109 molecule |
| Synonyms gene name | CD109 antigen (Gov platelet alloantigens) |
| Synonyms | FLJ38569 DKFZp762L1111 CPAMD7 |
| Locus | 6q13 |
| Discovery year | 2003-07-04 |
| GenBank acession | AF410459 |
| Entrez gene record | 135228 |
| Pubmed identfication | 11861284 11861285 |
| RefSeq identity | NM_133493 |
| Classification | CD molecules C3 and PZP like, alpha-2-macroglobulin domain containing |
| Havana BLAST/BLAT | OTTHUMG00000015040 |
| Locus Specific Databases | LRG_1002 |