| Also known as | CD11a |
| Other names | CD11 antigen-like family member A, CD11 antigen-like family member A, CD_antigen: CD11a, Integrin alpha-L, LFA-1 alpha, LFA-1A, LFA-1A, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain, alpha L (antigen CD11A (p180), alpha polypeptide, alpha polypeptide), antigen CD11A (p180), integrin, integrin alpha-L, integrin gene promoter, leukocyte adhesion glycoprotein LFA-1 alpha chain, leukocyte function-associated molecule 1 alpha chain, lymphocyte function-associated antigen 1, lymphocyte function-associated antigen 1, lymphocyte function-associated antigen 1, integrin alpha-L isoform b |
| Category | Antibodies |
| Subcategory | Mnoclonal antibodies |
| Gene name | ITGAL |
| Gene name synonims | N/A |
| Other gene names | CD11A, CD11A, ITGAL, LFA-1, LFA-1A, LFA1A, ITGAL |
| Clonality | Monoclonal |
| Immunoglobulin isotype | kappa, IgG2b |
| Clone | CRIS-3 |
| Host organism | Mouse (Mus musculus) |
| Species reactivity | Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity | CD11a complex with the ?2 subunit of the integrin family, CD18, Code N202), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses, It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), LFA-1 is expressed on all leukocytes including lymphocytes, LFA-1 or CD11a /C18 (aLbL), Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, and granulocytes, identified as CD11a (Leucocyte Workshop II, monocytes, to form the cell surface heterodimer, Recognizes a protein of 180kDa |
| Purification method | N/A |
| Form/Appearance | N/A |
| Concentration | N/A |
| Storage and shipping | Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications: | Flow Cytometry (FC/FACS), Functional Studies, Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), ELISA (EIA) |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target | CD11a |
| Short name | CD11a Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CD11a (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6148 |
| Gene | ITGAL |
| Long gene name | integrin subunit alpha L |
| Synonyms gene | CD11A |
| Synonyms gene name | alpha L (antigen CD11A (p180), alpha polypeptide) , integrin, lymphocyte function-associated antigen 1 |
| Synonyms | LFA-1 |
| Synonyms name | alpha polypeptide , antigen CD11A (p180) lymphocyte function-associated antigen 1 |
| Locus | 16p11, 2 |
| Discovery year | 1986-01-01 |
| Entrez gene record | 3683 |
| Pubmed identfication | 3284962 |
| Classification | Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000176964 |