| Category | Antibody |
| Concentration | 09% sodium azide, 4 with 0, In 1X PBS pH 7 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | CD11c |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, IF, IHC, WB, FACS |
| Recommended dilutions | Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the CD11c antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This CD11c antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P20702 |
| Purity | Antigen affinity |
| Description | Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain, The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4), and in the phagocytosis of complement coated particles, ITGAX is the integrin alpha X chain protein |
| Immunogen | A portion of amino acids 1119-1145 from the human protein was used as the immunogen for this CD11c antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CD11c antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | CD11c |
| Short name | CD11c Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CD11c (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6152 |
| Gene | ITGAX |
| Long gene name | integrin subunit alpha X |
| Synonyms gene | CD11C |
| Synonyms gene name | alpha X (antigen CD11C (p150), alpha X (complement component 3 receptor 4 subunit) , alpha polypeptide) integrin, integrin |
| Synonyms | CD11c |
| Synonyms name | complement component 3 receptor 4 subunit |
| Locus | 16p11, 2 |
| Discovery year | 1988-08-15 |
| GenBank acession | BC038237 |
| Entrez gene record | 3687 |
| Pubmed identfication | 3284962 2303426 |
| RefSeq identity | NM_000887 |
| Classification | Complement system Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000132465 |