Name : CD153 Antibody
Supplier : NJS POLY
Price :406
SKU : GEN6233290494
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | CD153 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | IHC-P |
| Recommended dilutions | 5-1ug/ml, IHC (Paraffin): 0 |
| Notes | Optimal dilution of the CD153 antibody should be determined by the researcher |
| Intented use | This CD153 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P32971 |
| Purity | Antigen affinity |
| Description | The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch, The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas, The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family, This cytokine is a ligand for TNFRSF8/CD30, This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, Two transcript variants encoding different isoforms have been found for this gene, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies, while to induce cell death and reduce cell proliferation of other lymphoma cell lines, CD153 is a ligand for CD30 |
| Immunogen | Amino acids 63-234 of human CD153 were used as the immunogen for the CD153 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CD153 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization | membrane, Cytoplasmic |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | CD153 |
| Short name | CD153 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CD153 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11938 |
| Gene | TNFSF8 |
| Long gene name | tumor necrosis factor superfamily member 8 |
| Synonyms gene | CD30LG |
| Synonyms gene name | member 8 , tumor necrosis factor (ligand) superfamily |
| Synonyms | CD153 |
| Locus | 9q32-q33, 1 |
| Discovery year | 1993-11-08 |
| GenBank acession | L09753 |
| Entrez gene record | 944 |
| Pubmed identfication | 8391931 9349718 |
| Classification | Tumor necrosis factor superfamily CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000021025 |