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CD22/BLCAM Antibody

CD22/BLCAM Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCD22/BLCAM Primary Polyclonal Antibody
Also known asCD22/BLCAM PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCD22/BLCAM
SpecificityThis is a highly specific antibody against CD22/BLCAM
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range710-760/847
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD22
Gene ID number933
Swiss ProtP20273
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Binds sialylated glycoproteins, May be involved in the localization of B-cells in lymphoid tissues, Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules, Preferentially binds to alpha-2, The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface, Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling, one of which is CD45, 6-linked sialic acid, Mediates B-cell B-cell interactions
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names B-cell receptor CD22, B-lymphocyte cell adhesion molecule, BL-CAM, CD22, SIGLEC-2, Sialic acid-binding Ig-like lectin 2, T-cell surface antigen Leu-14, SIGLEC2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCD22/BLCAM
Short nameCD22/BLCAM Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCD22 molecule/BLCAM (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CD22 and IDBG-44001 and ENSG00000012124 and 933, CD22 and IDBG-635610 and ENSBTAG00000011887 and 514582, Cd22 and IDBG-171574 and ENSMUSG00000030577 and 12483, Cell surfaces, SIGLEC-2 and SIGLEC2, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding, CD22 molecule
Identity 1643
Gene CD22
Long gene name CD22 molecule
Synonyms gene name CD22 antigen
Synonyms SIGLEC-2 SIGLEC2
Synonyms name sialic acid binding Ig-like lectin 2
Locus 19q13, 12
Discovery year 1991-06-06
GenBank acession X52785
Entrez gene record 933
Pubmed identfication 8496602 1691828
RefSeq identity NM_001771
Classification C2-set domain containing CD molecules Sialic acid binding Ig like lectins
Havana BLAST/BLAT OTTHUMG00000183298

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