| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | CD27 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, FACS, WB |
| Recommended dilutions | Flow Cytometry: 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the CD27 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This CD27 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P26842 |
| Purity | Antigen affinity |
| Description | Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor, CD27-binding protein (SIVA), It binds to ligand CD70, This receptor is required for generation and long-term maintenance of T cell immunity, This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK, a proapoptotic protein, and plays a key role in regulating B-cell activation and immunoglobulin synthesis, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor, The protein encoded by this gene is a member of the TNF-receptor superfamily |
| Immunogen | A portion of amino acids 196-225 from the human protein was used as the immunogen for this CD27 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CD27 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | CD27 |
| Short name | CD27 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CD27 molecule (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | CD27 and IDBG-14014 and ENSG00000139193 and 939, CD27 and IDBG-640494 and ENSBTAG00000014725 and 512514, Cd27 and IDBG-189750 and ENSMUSG00000030336 and 21940, Extracellular, LPFS2 and T14 and TNFRSF7 and Tp55, S152 and S152, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0008588 and release of cytoplasmic sequestered NF-kappaB and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0016064 and immunoglobulin mediated immune response and biological process this GO :0043027 and cysteine-type endopeptidase inhibitor activity involved in apoptotic process and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045471 and response to ethanol and biological process this GO :0045579 and positive regulation of B cell differentiation and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070233 and negative regulation of T cell apoptotic process and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process, this GO :0004888: transmembrane signaling receptor activity, this GO :0004888: transmembrane signaling receptor activity and also this GO :0005515: protein binding and also this GO :0043027: cysteine-type endopeptidase inhibitor activity involved in apoptotic process, this GO :0005515: protein binding, this GO :0043027: cysteine-type endopeptidase inhibitor activity involved in apoptotic process, CD27 molecule |
| Identity | 11922 |
| Gene | CD27 |
| Long gene name | CD27 molecule |
| Synonyms gene | TNFRSF7 |
| Synonyms gene name | member 7 , tumor necrosis factor receptor superfamily |
| Synonyms | S152 Tp55 |
| Locus | 12p13, 31 |
| Discovery year | 1992-06-10 |
| GenBank acession | M63928 |
| Entrez gene record | 939 |
| Pubmed identfication | 2442250 8530100 |
| Classification | CD molecules Tumor necrosis factor receptor superfamily |
| Havana BLAST/BLAT | OTTHUMG00000168316 |
| Locus Specific Databases | LRG_357 |