Name : CD2AP Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN3359632848
| Long name | CD2AP Primary Polyclonal Antibody |
| Also known as | CD2AP PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CD2AP |
| Specificity | This is a highly specific antibody against CD2AP |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 580-630/641 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD2AP |
| Gene ID number | 23607 |
| Swiss Prot | Q9Y5K6 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Also required for cytokinesis, Controls CBLC function, In collaboration with CBLC, May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus, May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell, converting it from an inhibitor to a promoter of RET degradation, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival, Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Adapter protein CMS, CD2-associated protein, CD2AP, Cas ligand with multiple SH3 domains, CMS |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CD2AP |
| Short name | CD2AP Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CD2 molecule-associated protein (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | CD2AP and IDBG-632396 and ENSBTAG00000000322 and 533188, CD2AP and IDBG-90083 and ENSG00000198087 and 23607, CMS, Cd2ap and IDBG-183950 and ENSMUSG00000061665 and 12488, Cell surfaces, SH3 domain binding, cell extension and biological process this GO :0007067 and mitotic nuclear division and biological process this GO :0007165 and signal transduction and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0017124 and SH3 domain binding and molecular function this GO :0031941 and filamentous actin and cellular component this GO :0032911 and negative regulation of transforming growth factor beta1 production and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :1900182 and positive regulation of protein localization to nucleus and biological process this GO :2000249 and regulation of actin cytoskeleton reorganization and biological process, this GO :0001726 and ruffle and cellular component this GO :0005200 and structural constituent of cytoskeleton and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006930 and substrate-dependent cell migration, this GO :0005200: structural constituent of cytoskeleton, this GO :0005200: structural constituent of cytoskeleton and also this GO :0005515: protein binding and also this GO :0017124: SH3 domain binding, this GO :0005515: protein binding, this GO :0017124: SH3 domain binding, CD2-associated protein |
| Identity | 14258 |
| Gene | CD2AP |
| Long gene name | CD2 associated protein |
| Synonyms | CMS |
| Locus | 6p12, 3 |
| Discovery year | 2000-12-14 |
| GenBank acession | AF146277 |
| Entrez gene record | 23607 |
| Pubmed identfication | 10339567 |
| Havana BLAST/BLAT | OTTHUMG00000014799 |