| Long name | CD3E Primary Polyclonal Antibody |
| Also known as | CD3E PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CD3E |
| Specificity | This is a highly specific antibody against CD3E |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 21-71/189 |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from mouse CD3 epsilon |
| Gene ID number | 12501 |
| Swiss Prot | P22646 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Rat, Mouse |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | The CD3 complex mediates signal transduction |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | AI504783, CD3e, CD3epsilon, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3e, CD3 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CD3E |
| Short name | CD3E Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | epsilon (CD3-TCR complex) (Antibody to), CD3e molecule |
| Alternative technique | antibodies |
| Alternative to gene target | CD3E and IDBG-631260 and ENSBTAG00000015710 and 281054, CD3E and IDBG-73617 and ENSG00000198851 and 916, Cd3e and IDBG-159085 and ENSMUSG00000032093 and 12501, Cell surfaces, IMD18 and T3E and TCRE, epsilon (CD3-TCR complex), protein heterodimerization activity, this GO :0001772 and immunological synapse and cellular component this GO :0002669 and positive regulation of T cell anergy and biological process this GO :0004871 and signal transducer activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005057 and receptor signaling protein activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007172 and signal complex assembly and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007584 and response to nutrient and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016020 and membrane and cellular component this GO :0017124 and SH3 domain binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030159 and receptor signaling complex scaffold activity and molecular function this GO :0031295 and T cell costimulation and biological process this GO :0032729 and positive regulation of interferon-gamma production and biological process this GO :0032753 and positive regulation of interleukin-4 production and biological process this GO :0033077 and T cell differentiation in thymus and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0042101 and T cell receptor complex and cellular component this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042105 and alpha-beta T cell receptor complex and cellular component this GO :0042110 and T cell activation and biological process this GO :0042608 and T cell receptor binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0045060 and negative thymic T cell selection and biological process this GO :0045086 and positive regulation of interleukin-2 biosynthetic process and biological process this GO :0045879 and negative regulation of smoothened signaling pathway and biological process this GO :0046641 and positive regulation of alpha-beta T cell proliferation and biological process this GO :0046649 and lymphocyte activation and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050776 and regulation of immune response and biological process this GO :0050850 and positive regulation of calcium-mediated signaling and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050870 and positive regulation of T cell activation and biological process this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0004871: signal transducer activity, this GO :0004871: signal transducer activity and also this GO :0004888: transmembrane signaling receptor activity and also this GO :0005057: receptor signaling protein activity and also this GO :0005515: protein binding and also this GO :0017124: SH3 domain binding and also this GO :0019901: protein kinase binding and also this GO :0030159: receptor signaling complex scaffold activity and also this GO :0042608: T cell receptor binding and also this GO :0046982: protein heterodimerization activity, this GO :0004888: transmembrane signaling receptor activity, this GO :0005057: receptor signaling protein activity, this GO :0005515: protein binding, this GO :0017124: SH3 domain binding, this GO :0019901: protein kinase binding, this GO :0030159: receptor signaling complex scaffold activity, this GO :0042608: T cell receptor binding, this GO :0046982: protein heterodimerization activity, CD3e molecule |
| Identity | 1674 |
| Gene | CD3E |
| Long gene name | CD3e molecule |
| Synonyms gene name | CD3e antigen, epsilon (CD3-TCR complex) , epsilon polypeptide (TiT3 complex) CD3e molecule |
| Locus | 11q23, 3 |
| Discovery year | 1986-01-01 |
| GenBank acession | X03884 |
| Entrez gene record | 916 |
| RefSeq identity | NM_000733 |
| Classification | CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000166968 |
| Locus Specific Databases | CD3Ebase: Mutation registry for autosomal recessive CD3epsilon immunodeficiency LRG_38 |
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