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CD43

CD43 size: 100ug 354

Supplier MBS MONO
Price 354
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD43
Other names CD43), CD_antigen: CD43, GALGP, Galactoglycoprotein, Leukocyte sialoglycoprotein, Leukosialin, Sialophorin, galactoglycoprotein, leukocyte sialoglycoprotein, leukosialin, leukosialin, sialophorin, sialophorin (gpL115, leukosialin
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameSPN
Gene name synonimsN/A
Other gene names CD43, CD43, GALGP, GALGP, GPL115, LSN, SPN, SPN
ClonalityMonoclonal
Immunoglobulin isotype kappa, IgG1
CloneSPM503
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43, Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma, No reactivity has been observed with reactive B-cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, This particular antibody might cross react with speacies outside of the listed ones, When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained, especially a low-grade lymphoma, identified as CD43, rather than a reactive B-cell population, It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation)
Purification methodN/A
Form/AppearanceN/A
ConcentrationN/A
Storage and shipping Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C
Tested applications: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), ELISA (EIA)
Gene targetCD43
Short nameCD43
Alternative nameCD43
Identity 11249
Gene SPN
Long gene name sialophorin
Synonyms gene name CD43) , leukosialin, sialophorin (gpL115
Synonyms LSN CD43 GPL115
Synonyms name leukosialin
Locus 16p11, 2
Discovery year 1988-08-31
GenBank acession J04536
Pubmed identfication 2784859 2521952
Classification CD molecules
Havana BLAST/BLAT OTTHUMG00000097765

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