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CD45RA

CD45RA size: 100ug 354

Supplier MBS MONO
Price 354
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD45RA
Other names C, CD45 antigen, CD_antigen: CD45, L-CA, Leukocyte common antigen, Receptor-type tyrosine-protein phosphatase C, T200, T200 glycoprotein, T200 leukocyte common antigen, c polypeptide, protein tyrosine phosphatase, protein tyrosine phosphatase, receptor type, receptor type, receptor-type tyrosine-protein phosphatase C, receptor-type tyrosine-protein phosphatase C isoform 1
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene namePTPRC
Gene name synonimsN/A
Other gene names B220, CD45, CD45, CD45R, GP180, L-CA, L-CA, LCA, LY5, PTPRC, T200, PTPRC
ClonalityMonoclonal
Immunoglobulin isotype kappa, IgG2a
Clone158-4D3
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity 50% of peripheral CD8+ T-cells, AB, ABC, B and C, B and O, B-cells, BC, CD45RA and CD45RO define complementary, CD45RA is expressed on 40-50% of peripheral CD4+ T-cells, CD45RA is isoforms of the human leukocyte common antigen (CD45), Human CD45 contains three exons which encode peptide segments designated A, It can especially be used to differentiate T-cell lymphomas (CD45RO +ve) from B cell lymphomas (CD45RA +ve), Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, T-cells expressing CD45RA are naive or virgin T-cells, T-cells expressing CD45RO are memory T-cells, The differential splicing of the exons generates at least five isoforms, This MAb is useful in study on the subpopulation of CD4+ or CD8+ T-cells, This antibody reacts with ABC and BC isoforms, This particular antibody might cross react with speacies outside of the listed ones, and leukemic B-cell lines, identified as CD45RA, predominantly non-overlapping populations of resting peripheral T-cells, respectively, Recognizes a protein of 205kDa-220kDa
Purification methodN/A
Form/AppearanceN/A
ConcentrationN/A
Storage and shipping Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C
Tested applications: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), ELISA (EIA)
Gene targetCD45RA
Short nameCD45RA
Alternative nameCD45RA

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