Name : CD82 Antibody
Supplier : NJS POLY
Price :389
SKU : GEN9822695350
| Category | Antibody |
| Concentration | 025% sodium azide, 2mg/ml in 1X PBS with 50% glycerol and 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | CD82 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | WB |
| Recommended dilutions | 5-1ug/ml, Western blot: 0 |
| Notes | Titration of the CD82 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use | This CD82 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P27701 |
| Purity | Antigen affinity |
| Description | And the CD82 overexpression can suppress tumor invasiveness and metastatic potential by inducing MMP9 inactivation via upregulation of TIMP1, Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter, The expression of CD82 protein appears to be correlated with lymph node metastasis in esophageal squamous cell carcinoma(ESCC), The gene is mapped to 11p11, This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily, also named KAI1, is a human protein encoded by the CD82 gene, 2, CD82(Cluster of Differentiation 82) |
| Immunogen | An amino acid sequence from the C-terminus of human CD82 (CRHVHSEDYSKVPKY) was used as the immunogen for this CD82 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Store the CD82 antibody at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | CD82 |
| Short name | CD82 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CD82 molecule (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | 4F9 and C33 and GR15 and IA4 and KAI1 and R2 and SAR2 and ST6 and TSPAN27, CD82 and IDBG-40873 and ENSG00000085117 and 3732, CD82 and IDBG-636903 and ENSBTAG00000031252 and 100335281, Cd82 and IDBG-192552 and ENSMUSG00000027215 and 12521, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515: protein binding, this GO :0005515: protein binding, 506713, CD82 molecule |
| Identity | 6210 |
| Gene | CD82 |
| Long gene name | CD82 molecule |
| Synonyms gene | ST6 KAI1 |
| Synonyms gene name | CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)) CD82 antigen , kangai 1 (suppression of tumorigenicity 6, prostate |
| Synonyms | R2 IA4 TSPAN27 |
| Synonyms name | suppression of tumorigenicity 6 R2 leukocyte antigen |
| Locus | 11p11, 2 |
| Discovery year | 1994-01-10 |
| GenBank acession | U20770 |
| Entrez gene record | 3732 |
| Classification | CD molecules Tetraspanins |
| Havana BLAST/BLAT | OTTHUMG00000166472 |