| Long name | CD86 Primary Polyclonal Antibody |
| Also known as | CD86 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CD86 |
| Specificity | This is a highly specific antibody against CD86 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 130-180/313 |
| Subcellular location | Intracellular, Membrane bound |
| Source | KLH conjugated synthetic peptide derived from rat CD86 |
| Gene ID number | 56822 |
| Swiss Prot | O35531 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Alternative splicing results in several transcript variants encoding different isoforms, Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell, Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4, May 2011], This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily, [provided by RefSeq |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Cd86, Cd86 antigen, Membrane glycoprotein, B7-2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CD86 |
| Short name | CD86 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CD86 molecule (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | B7-2 and B7, CD86 and IDBG-52336 and ENSG00000114013 and 942, CD86 and IDBG-633264 and ENSBTAG00000013118 and 414345, Cd86 and IDBG-158071 and ENSMUSG00000022901 and 12524, Cell surfaces, DNA-templated and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0051607 and defense response to virus and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071248 and cellular response to metal ion and biological process this GO :0071345 and cellular response to cytokine stimulus and biological process, coreceptor activity, this GO :0001878 and response to yeast and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002309 and T cell proliferation involved in immune response and biological process this GO :0002668 and negative regulation of T cell anergy and biological process this GO :0004872 and receptor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007568 and aging and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0015026 and coreceptor activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0031295 and T cell costimulation and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0034341 and response to interferon-gamma and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042104 and positive regulation of activated T cell proliferation and biological process this GO :0042110 and T cell activation and biological process this GO :0042113 and B cell activation and biological process this GO :0042493 and response to drug and biological process this GO :0043011 and myeloid dendritic cell differentiation and biological process this GO :0043017 and positive regulation of lymphotoxin A biosynthetic process and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0045086 and positive regulation of interleukin-2 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045404 and positive regulation of interleukin-4 biosynthetic process and biological process this GO :0045630 and positive regulation of T-helper 2 cell differentiation and biological process this GO :0045893 and positive regulation of transcription, this GO :0004872: receptor activity, this GO :0004872: receptor activity and also this GO :0005102: receptor binding and also this GO :0005515: protein binding and also this GO :0015026: coreceptor activity, this GO :0005102: receptor binding, this GO :0005515: protein binding, this GO :0015026: coreceptor activity, 2 and B70 and CD28LG2 and LAB72, CD86 molecule |
| Identity | 1705 |
| Gene | CD86 |
| Long gene name | CD86 molecule |
| Synonyms gene | CD28LG2 |
| Synonyms gene name | B7-2 antigen) , CD86 antigen (CD28 antigen ligand 2 |
| Synonyms | B7, 2 B7-2 |
| Synonyms name | B-lymphocyte antigen B7-2 |
| Locus | 3q13, 33 |
| Discovery year | 1994-12-07 |
| Entrez gene record | 942 |
| Pubmed identfication | 7513726 |
| RefSeq identity | NM_006889 |
| Classification | Immunoglobulin like domain containing CD molecules V-set domain containing |
| Havana BLAST/BLAT | OTTHUMG00000159482 |
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