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CD8A Antibody

CD8A Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCD8A
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IHC, WB
Recommended dilutionsIHC (Paraffin): 1:10-1:50, Western blot: 1:1000
NotesTitration of the CD8A antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis CD8A antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P01732
PurityAntigen affinity
Description CD8 alpha chains binds to class I MHC molecules alpha-3 domains, [UniProt], CD8 is thought to play a role in the process of T-cell mediated killing
ImmunogenA portion of amino acids 59-88 from the human protein was used as the immunogen for this CD8A antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CD8A antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCD8A
Short nameCD8A Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCD8a molecule (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CD8 and Leu2 and MAL and p32, CD8A and IDBG-59987 and ENSG00000153563 and 925, CD8A and IDBG-634911 and ENSBTAG00000021141 and 281060, Cd8a and IDBG-155582 and ENSMUSG00000053977 and 12525, Extracellular, protein homodimerization activity, this GO :0002456 and T cell mediated immunity and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0015026 and coreceptor activity and molecular function this GO :0016020 and membrane and cellular component this GO :0019882 and antigen processing and presentation and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0042101 and T cell receptor complex and cellular component this GO :0042110 and T cell activation and biological process this GO :0042288 and MHC class I protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0045065 and cytotoxic T cell differentiation and biological process this GO :0045087 and innate immune response and biological process this GO :0050776 and regulation of immune response and biological process this GO :0050850 and positive regulation of calcium-mediated signaling and biological process this GO :0051607 and defense response to virus and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0015026: coreceptor activity and also this GO :0019901: protein kinase binding and also this GO :0042288: MHC class I protein binding and also this GO :0042803: protein homodimerization activity, this GO :0015026: coreceptor activity, this GO :0019901: protein kinase binding, this GO :0042288: MHC class I protein binding, this GO :0042803: protein homodimerization activity, CD8a molecule
Identity 1706
Gene CD8A
Long gene name CD8a molecule
Synonyms gene CD8
Synonyms gene name CD8 antigen, alpha polypeptide (p32) T-cell surface glycoprotein CD8 alpha chain
Locus 2p11, 2
Discovery year 1986-01-01
Entrez gene record 925
Pubmed identfication 1541829
RefSeq identity NM_001768
Classification CD molecules V-set domain containing
Havana BLAST/BLAT OTTHUMG00000130265
Locus Specific Databases CD8Abase: Mutation registry for CD8 deficiency LRG_44

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