| Long name | CD95 Primary Polyclonal Antibody |
| Also known as | CD95 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CD95 |
| Specificity | This is a highly specific antibody against CD95 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 20-70/327 |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from mouse FAS |
| Gene ID number | 14102 |
| Swiss Prot | P25446 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Rat, Mouse |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, The adapter molecule FADD recruits caspase-8 to the activated receptor, The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis, in the antigen-stimulated suicide of mature T-cells, or both (By similarity), Receptor for TNFSF6/FASLG |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | AI196731, APO1, APT1, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, CD95, FASLG receptor, Fas, TNFR6, Tnfrsf6, Tumor necrosis factor receptor superfamily member 6, lpr |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CD95 |
| Short name | CD95 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CD95 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11920 |
| Gene | FAS |
| Long gene name | Fas cell surface death receptor |
| Synonyms gene | FAS1 APT1 TNFRSF6 |
| Synonyms gene name | member 6 Fas (TNF receptor superfamily, member 6) , tumor necrosis factor receptor superfamily |
| Synonyms | CD95 APO-1 |
| Synonyms name | TNF receptor superfamily member 6 |
| Locus | 10q23, 31 |
| Discovery year | 1992-06-25 |
| GenBank acession | M67454 |
| Entrez gene record | 355 |
| Pubmed identfication | 1385299 1385309 |
| Classification | CD molecules Tumor necrosis factor receptor superfamily Death inducing signaling complex |
| Havana BLAST/BLAT | OTTHUMG00000018701 |
| Locus Specific Databases | Autoimmune Lymphoproliferative Syndrome Database (ALPSbase): Database of mutations causing human ALPS LOVD at NCBI LRG_134 |
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