CDKN2B Antibody

CDKN2B Antibody size: 0.08 ml 199

Price 199

Size 0.08 ml

Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit

Category	Antibody
Concentration	pH 7, with 0, 09% sodium azide, 4, In 1X PBS
Form	Antigen affinity purified
Conjugation	Unconjugated
Clone	Polyclonal antibody
Recognised antigen	CDKN2B
Host animal	Rabbit (Oryctolagus cuniculus)
Clonality	Polyclonal (rabbit origin)
Species reactivity	Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications	ELISA, FACS, IF, IHC, WB
Recommended dilutions	Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
Notes	Titration of the CDKN2B antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented use	This CDKN2B antibodyis to be used only for research purposes and not for diagnostics
Uniprot #	P42772
Purity	Antigen affinity
Description	The expression of this gene was found to be dramatically induced by TGF beta, This gene encodes a cyclin-dependent kinase inhibitor, Two alternatively spliced transcript variants of this gene, and prevents the activation of the CDK kinases, have been reported, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression, which encode distinct proteins, which forms a complex with CDK4 or CDK6, which suggested its role in the TGF beta induced growth inhibition, This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors
Immunogen	A portion of amino acids 1-30 from the human protein was used as the immunogen for this CDKN2B antibody
Storage	Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CDKN2B antibody and store frozen at -20 deg
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target	CDKN2B
Short name	CDKN2B Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	inhibits cyclin-dependent kinase 4) (Antibody to), cyclin-dependent kinase inhibitor 2B (p15
Alternative technique	antibodies
Alternative to gene target	BT, CDK4I and INK4B and MTS2 and P15 and p15INK4b and TP15, CDKN2B and IDBG-54658 and ENSG00000147883 and 1030, Cdkn2b and IDBG-162957 and ENSMUSG00000073802 and 12579, DNA-templated and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007093 and mitotic cell cycle checkpoint and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007568 and aging and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0010467 and gene expression and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030219 and megakaryocyte differentiation and biological process this GO :0030511 and positive regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0030858 and positive regulation of epithelial cell differentiation and biological process this GO :0031668 and cellular response to extracellular stimulus and biological process this GO :0031670 and cellular response to nutrient and biological process this GO :0034097 and response to cytokine and biological process this GO :0042326 and negative regulation of phosphorylation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048536 and spleen development and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0071901 and negative regulation of protein serine/threonine kinase activity and biological process this GO :2000134 and negative regulation of G1/S transition of mitotic cell cycle and biological process, inhibits CDK4), nuclei, protein kinase binding, this GO :0000079 and regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0000086 and G2/M transition of mitotic cell cycle and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0001889 and liver development and biological process this GO :0004861 and cyclin-dependent protein serine/threonine kinase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0004861: cyclin-dependent protein serine/threonine kinase inhibitor activity, this GO :0004861: cyclin-dependent protein serine/threonine kinase inhibitor activity and also this GO :0005515: protein binding and also this GO :0019901: protein kinase binding, this GO :0005515: protein binding, this GO :0019901: protein kinase binding, 45725 and IDBG-630040 and ENSBTAG00000016412 and 527124, cyclin-dependent kinase inhibitor 2B (p15
Identity	1788
Gene	CDKN2B
Long gene name	cyclin dependent kinase inhibitor 2B
Synonyms gene name	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
Synonyms	P15 MTS2 INK4B TP15 CDK4I p15INK4b
Locus	9p21, 3
Discovery year	1995-06-14
GenBank acession	AB060808
Entrez gene record	1030
Pubmed identfication	8078588
RefSeq identity	NM_004936
Havana BLAST/BLAT	OTTHUMG00000019691

CDKN2B Antibody

CDKN2B Antibody size: 0.08 ml 199

Similar products

Subscribe to our Newsletter