Name : CEBPB Antibody
Supplier : NJS POLY
Price :199
SKU : GEN4927912444
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | CEBPB |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, FACS, IHC, WB |
| Recommended dilutions | Flow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes | Titration of the CEBPB antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This CEBPB antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P17676 |
| Purity | Purified |
| Description | CEBP-delta, In addition, It can also form heterodimers with the related proteins CEBP-alpha, It can bind the promoter and upstream element and stimulate the expression of the collagen type I gene, This protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, and CEBP-gamma, as well as to regulatory regions of several acute-phase and cytokine genes, CEBPB is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions |
| Immunogen | A portion of amino acids 271-298 from the human protein was used as the immunogen for this CEBPB antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CEBPB antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | CEBPB |
| Short name | CEBPB Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | b (Antibody to), CCAAT/enhancer binding protein (C/EBP) |
| Alternative technique | antibodies |
| Alternative to gene target | C/EBP-beta and IL6DBP and NF-IL6 and TCF5, CEBPB and IDBG-80858 and ENSG00000172216 and 1051, Cebpb and IDBG-213090 and ENSMUSG00000056501 and 12608, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006953 and acute-phase response and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0016363 and nuclear matrix and cellular component this GO :0030182 and neuron differentiation and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0033598 and mammary gland epithelial cell proliferation and biological process this GO :0034976 and response to endoplasmic reticulum stress and biological process this GO :0035259 and glucocorticoid receptor binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045408 and regulation of interleukin-6 biosynthetic process and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0045600 and positive regulation of fat cell differentiation and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0050873 and brown fat cell differentiation and biological process this GO :0060644 and mammary gland epithelial cell differentiation and biological process this GO :0060850 and regulation of transcription involved in cell fate commitment and biological process this GO :0071230 and cellular response to amino acid stimulus and biological process, beta, centromeric region and cellular component this GO :0000790 and nuclear chromatin and cellular component this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001892 and embryonic placenta development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006355 and regulation of transcription, nuclei, protein heterodimerization activity, this GO :0000779 and condensed chromosome, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003705: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0035259: glucocorticoid receptor binding and also this GO :0042803: protein homodimerization activity and also this GO :0043565: sequence-specific DNA binding and also this GO :0046982: protein heterodimerization activity, this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677: DNA binding, this GO :0003682: chromatin binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003705: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0035259: glucocorticoid receptor binding, this GO :0042803: protein homodimerization activity, this GO :0043565: sequence-specific DNA binding, this GO :0046982: protein heterodimerization activity, CCAAT/enhancer binding protein (C/EBP) |
| Identity | 1834 |
| Gene | CEBPB |
| Long gene name | CCAAT/enhancer binding protein beta |
| Synonyms gene | TCF5 |
| Synonyms gene name | CCAAT/enhancer binding protein (C/EBP), beta |
| Synonyms | LAP CRP2 NFIL6 IL6DBP C/EBP-beta |
| Synonyms name | liver-enriched transcriptional activator protein nuclear factor of interleukin 6 interleukin 6-dependent DNA-binding protein |
| Locus | 20q13, 13 |
| Discovery year | 1991-02-27 |
| GenBank acession | AY193834 |
| Entrez gene record | 1051 |
| Pubmed identfication | 1535333 1840554 |
| RefSeq identity | NM_005194 |
| Classification | CCAAT/enhancer binding proteins Basic leucine zipper proteins |
| Havana BLAST/BLAT | OTTHUMG00000032715 |