Name : Cell permeable Inhibitor of EGFR2/FGFR/PDGFr/JAK1/Her2 ((E)-4-((4-)1H-1,2,3-Triazol-1-yl)butyl)phenoxy)methyl)-2-(4-trifluoromethyl)oxazole, mol wt 468; >98%)
Supplier : ADI
Price :188
SKU : GEN3901316099
| ELISA kit stock availability | Available In Stock |
| ELISA's description | >, mol wt 468, 2, 3-Triazol-1-yl)butyl)phenoxy)methyl)-2-(4-trifluoromethyl)oxazole, 98%), Cell permeable Inhibitor of EGFR2/FGFR/PDGFr/JAK1/Her2 ((E)-4-((4-)1H-1 |
| Category | Custom Service |
| S type | n/a |
| Antibody's host is | see techfile |
| Purification | Affinity purified |
| Description | Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , activator, caspase, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme,  , Tissue, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins  |
| Gene target | >, mol wt 468, 2, 3-Triazol-1-yl)butyl)phenoxy)methyl) 2 (4-trifluoromethyl)oxazole, 98%, permeable Inhibitor of EGFR2/FGFR/PDGFr/JAK1/Her2 (E) 4 (4 )1H-1 |
| Short name | >, mol wt 468, 2, 3-Triazol-1-yl)butyl)phenoxy)methyl)-2-(4-trifluoromethyl)oxazole, 98%), Cell permeable Inhibitor of EGFR2/FGFR/PDGFr/JAK1/Her2 ((E)-4-((4-)1H-1 |
| Alternative name | >, mol wt 468, 2, 3-Triazol-1-yl)butyl)phenoxy)methyl)-2-(4-trifluoromethyl)oxazole, 98%), cellular permeable suppressor on EGFR2/FGFR/PDGFr/Janus kinase 1/Her2 ((E)-4-((4-)1H-1 |
| Alternative to gene target | JAK1 and IDBG-638346 and ENSBTAG00000003147 and 537201, JAK1 and IDBG-99443 and ENSG00000162434 and 3716, JAK1A and JAK1B and JTK3, Jak1 and IDBG-167366 and ENSMUSG00000028530 and 16451, nuclei, this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0005131 and growth hormone receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007167 and enzyme linked receptor protein signaling pathway and biological process this GO :0012505 and endomembrane system and cellular component this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004715: non-membrane spanning protein tyrosine kinase activity and also this GO :0005131: growth hormone receptor binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004715: non-membrane spanning protein tyrosine kinase activity, this GO :0005131: growth hormone receptor binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0019903: protein phosphatase binding, this GO :0031730: CCR5 chemokine receptor binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019903: protein phosphatase binding and also this GO :0031730: CCR5 chemokine receptor binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019903 and protein phosphatase binding and molecular function this GO :0031730 and CCR5 chemokine receptor binding and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0038110 and interleukin-2-mediated signaling pathway and biological process this GO :0045087 and innate immune response and biological process this GO :0046677 and response to antibiotic and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060334 and regulation of interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0060338 and regulation of type I interferon-mediated signaling pathway and biological process, Janus kinase 1 |
| Identity | 6190 |
| Gene | JAK1 |
| Long gene name | Janus kinase 1 |
| Synonyms gene | JAK1B |
| Synonyms | JAK1A JTK3 |
| Locus | 1p31, 3 |
| Discovery year | 1992-04-16 |
| GenBank acession | M64174 |
| Entrez gene record | 3716 |
| Pubmed identfication | 1848670 7698020 |
| RefSeq identity | NM_002227 |
| Classification | FERM domain containing |
| Havana BLAST/BLAT | OTTHUMG00000009310 |