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CELSR2 Antibody

CELSR2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCELSR2 Primary Polyclonal Antibody
Also known asCELSR2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCELSR2
SpecificityThis is a highly specific antibody against CELSR2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CELSR2
Tested Applications IF(IHC-P), IHC-P, FCM
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), FCM(1:20-100)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CELSR1, CELSR2 and CELSR3 are expressed in the nervous system at early developmental stages, CELSR2 is distributed at intercellular boundaries in the whisker and on processes of neuronal cells such as hippocampal pyramidal cells, Cadherin EGF LAG seven pass G-type receptors (CELSRs) are multi-pass membrane proteins that belong to the G protein-coupled receptor family of proteins, Flamingo mammalian homo-logs play similar roles in neuronal development, In mouse, Purkinje cells and olfactory neurons, Silencing CELSR2 gene ex-pression results in signficant simplification of dendritic arbors of cortical pyramidal neurons and Purkinje neurons, and show expression patterns in the developing CNS, during which they play an important role in cell-cell signaling, which may be due to branch retraction, Drosophila Flamingo is a seven pass transmembrane cadherin that is necessary for dendritic patterning and axon guidance
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CDHF10, CELR2_HUMAN, Cadherin EGF LAG seven-pass G-type receptor 2, Cadherin family member 10, Celsr2, EGF like domain multiple 2, EGF-like protein 2, EGFL2, Epidermal growth factor-like protein 2, Flamingo homolog 3, Flamingo1, KIAA0279, MEGF3, Multiple EGF-like domains protein 3, Multiple epidermal growth factor-like domains protein 3, epidermal growth factor like 2, Cadherin EGF LAG seven pass G type receptor 2 flamingo Drosophila homolog
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCELSR2
Short nameCELSR2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name Drosophila) (Antibody to), epidermal growth factor LAG seven-pass G-classification receptor 2 (flamin this GO homolog, cadherin
Alternative techniqueantibodies
Alternative to gene target BT, CDHF10 and EGFL2 and Flamin this GO 1 and MEGF3, CELSR2 and IDBG-100797 and ENSG00000143126 and 1952, Celsr2 and IDBG-187099 and ENSMUSG00000068740 and 53883, DNA-templated and biological process this GO :0007156 and homophilic cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007218 and neuropeptide signaling pathway and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016055 and Wnt signaling pathway and biological process this GO :0021591 and ventricular system development and biological process this GO :0021999 and neural plate anterior/posterior regionalization and biological process this GO :0022407 and regulation of cell-cell adhesion and biological process this GO :0032880 and regulation of protein localization and biological process this GO :0033326 and cerebrospinal fluid secretion and biological process this GO :0042384 and cilium assembly and biological process this GO :0048813 and dendrite morphogenesis and biological process, Drosophila), EGF LAG seven-pass G-type receptor 2 (flamin this GO homolog, Plasma membranes, protein binding, this GO :0001764 and neuron migration and biological process this GO :0003341 and cilium movement and biological process this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006355 and regulation of transcription, this GO :0004888: transmembrane signaling receptor activity, this GO :0004888: transmembrane signaling receptor activity and also this GO :0004930: G-protein coupled receptor activity and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding, this GO :0004930: G-protein coupled receptor activity, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, 105016 and IDBG-635487 and ENSBTAG00000018804 and 538194, cadherin
Identity 3231
Gene CELSR2
Long gene name cadherin EGF LAG seven-pass G-type receptor 2
Synonyms gene EGFL2
Synonyms gene name EGF LAG seven-pass G-type receptor 2, EGF LAG seven-pass G-type receptor 2 , cadherin, flamingo (Drosophila) homolog cadherin
Synonyms KIAA0279 MEGF3 Flamingo1 CDHF10 ADGRC2
Synonyms name adhesion G protein-coupled receptor C2
Locus 1p13, 3
Discovery year 1998-03-25
GenBank acession D87469
Entrez gene record 1952
Pubmed identfication 9693030 10907856
RefSeq identity NM_001408
Classification CELSR cadherins Adhesion G protein-coupled receptors, subfamily C
Havana BLAST/BLAT OTTHUMG00000012003

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