Name : CFP Antibody
Supplier : NJS POLY
Price :199
SKU : GEN3629240472
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | CFP |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, FACS, WB |
| Recommended dilutions | Flow Cytometry: 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the CFP antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This CFP antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P27918 |
| Purity | Antigen affinity |
| Description | Mutations in this gene result in two forms of properdin deficiency, This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell, which results in high susceptibility to meningococcal infections, This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system |
| Immunogen | A portion of amino acids 197-223 from the human protein was used as the immunogen for this CFP antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CFP antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | CFP |
| Short name | CFP Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | complement factor properdin (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BFD and PFC and PFD and PROPERDIN, CFP and IDBG-61793 and ENSG00000126759 and 5199, CFP and IDBG-636742 and ENSBTAG00000015815 and 539605, Cfp and IDBG-135734 and ENSMUSG00000001128 and 18636, Extracellular, alternative pathway and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0042742 and defense response to bacterium and biological process this GO :0045087 and innate immune response and biological process, this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006955 and immune response and biological process this GO :0006956 and complement activation and biological process this GO :0006957 and complement activation, complement factor properdin |
| Identity | 8864 |
| Gene | CFP |
| Long gene name | complement factor properdin |
| Synonyms gene | PFC |
| Synonyms gene name | complement , properdin P factor |
| Locus | Xp11, 23 |
| Discovery year | 1989-06-07 |
| GenBank acession | M83652 |
| Entrez gene record | 5199 |
| Pubmed identfication | 1783405 |
| RefSeq identity | NM_002621 |
| Classification | Complement system |
| Havana BLAST/BLAT | OTTHUMG00000021451 |
| Locus Specific Databases | PFCbase: Mutation registry for properdin deficiency Mental Retardation database LRG_129 |