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CHFR Antibody

CHFR Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCHFR Primary Polyclonal Antibody
Also known asCHFR PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCHFR
SpecificityThis is a highly specific antibody against CHFR
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CHFR
Gene ID number55743
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 40% of primary colorectal cancers, 53% of colorectal adenomas, CHFR contains a cysteine-rich region that did not display significant similarity to any protein in the GenBank database, It has a FHA and ring finger domain within its N terminus, It has been concluded that CHFR defines a checkpoint that delays entry into metaphase in response to mitotic stress, It has been found CpG methylation-dependent silencing of CHFR expression occurs in 45% of cancer cell lines, Many proteins that contain forkhead-associated (FHA) domains are cell cycle checkpoints and CHFR is one such protein, Within its C terminus, and 30% of primary head and neck cancers, but is highly conserved between humans and mice, implying checkpoint defects, A number of human cancers are sensitive to mitotic stress
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CHFR_HUMAN, Checkpoint with forkhead and RING finger domains protein, E3 ubiquitin protein ligase CHFR, EC 6, RING finger protein 196, RNF 116, RNF 196, RNF116, RNF196, Ubiquitin ligase protein, 2, 3, Checkpoint with forkhead and ring finger domains
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCHFR
Short nameCHFR Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCHFR (Antibody to)
Alternative techniqueantibodies
Identity 20455
Gene CHFR
Long gene name checkpoint with forkhead and ring finger domains
Synonyms gene name E3 ubiquitin protein ligase , checkpoint with forkhead and ring finger domains checkpoint with forkhead and ring finger domains
Synonyms FLJ10796 RNF196
Locus 12q24, 33
Discovery year 2003-02-14
GenBank acession AK001658
Entrez gene record 55743
Pubmed identfication 10935642 11807090
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000167930

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