Name : CHMP4B+CHMP4C Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN2613498723
| Long name | ALEXA FLUOR 488 Conjugated, CHMP4B+CHMP4C Polyclonal Antibody |
| Also known as | Anti-CHMP4B+CHMP4C PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | CHMP4B+CHMP4C |
| Specificity | This is a highly specific antibody against CHMP4B+CHMP4C |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 95-137/224 |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CHMP4B/CHMP4C |
| Gene ID Number | 92421, 128866 |
| Swiss Prot | Q96CF2, Q9H444 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | -I, ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released, MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, The ESCRT machinery also functions in topologically equivalent membrane fission events, The MVB pathway appears to require the sequential function of ESCRT-O, lysosomal enzymes and lipids, such as stimulated growth factor receptors, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses), -II and -III complexes, Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | dJ553F4, 4 Shax1 SNF7-2 VPS32B |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CHMP4B+CHMP4C Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | CHMP4B+CHMP4C |
| Short name | CHMP4B+CHMP4C Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, CHMP4B+CHMP4C (Antibody to) |
| Alternative technique | antibodies |
| Identity | 16171 |
| Gene | CHMP4B |
| Long gene name | charged multivesicular body protein 4B |
| Synonyms gene | C20orf178 |
| Synonyms gene name | chromosome 20 open reading frame 178 chromatin modifying protein 4B |
| Locus | 20q11, 22 |
| Discovery year | 2001-07-17 |
| GenBank acession | AL050349 |
| Entrez gene record | 128866 |
| Pubmed identfication | 14678797 |
| Classification | Charged multivesicular body proteins ESCRT-III |
| Havana BLAST/BLAT | OTTHUMG00000032272 |