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Chromogranin A

Chromogranin A size: 100ug 354

Supplier MBS MONO
Price 354
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asChromogranin A
Other names Chromogranin-A, Pituitary secretory protein I, SP-I, SP-I, betagranin (N-terminal fragment of chromogranin A), catestatin, chromofungin, chromogranin A (parathyroid secretory protein 1), chromogranin-A, parathyroid secretory protein 1, pituitary secretory protein I, chromogranin-A isoform 1 preproprotein
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCHGA
Gene name synonimsN/A
Other gene names CGA, CHGA, CgA, SP-I, CHGA
ClonalityMonoclonal
Immunoglobulin isotype kappa, IgG1
CloneSPM585
Host organismMouse (Mus musculus)
Species reactivity Does not react with Mouse (Mus musculus) and Rat (Rattus norvegicus), Due to limited knowledge and inability for testing each and every species, Monkey, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms, It is an excellent marker for carcinoid tumors, Most pituitary adenomas and prolactinomas readily express chromogranin, Reportedly, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms, The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma, This particular antibody might cross react with speacies outside of the listed ones, adrenal medulla and pancreatic islets, and other neuroendocrine tumors, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage, including the neuroendocrine cells of the large and small intestine, paragangliomas, pheochromocytomas, Chromogranin A is present in neuroendocrine cells throughout the body
Purification methodN/A
Form/AppearanceN/A
ConcentrationN/A
Storage and shipping Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C
Tested applications: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), ELISA (EIA)
Gene targetChromogranin A
Short nameChromogranin A
Alternative nameChromogranin A
Identity 1929
Gene CHGA
Long gene name chromogranin A
Synonyms name vasostatin pancreastatin parastatin parathyroid secretory protein 1
Locus 14q32, 12
Discovery year 2001-06-22
Entrez gene record 1113
Pubmed identfication 3403545
RefSeq identity NM_001275
Classification Granins
Havana BLAST/BLAT OTTHUMG00000171225

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