Name : cIAP2 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN7988913188
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | cIAP2 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, IHC, WB |
| Recommended dilutions | IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the cIAP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This cIAP2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q13489 |
| Purity | Antigen affinity |
| Description | The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain, The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals, probably by interfering with activation of ICE-like proteases, BIRC3 is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 |
| Immunogen | A portion of amino acids 101-131 from the human protein was used as the immunogen for this cIAP2 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the cIAP2 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | cIAP2 |
| Short name | cIAP2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | cIAP2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 591 |
| Gene | BIRC3 |
| Long gene name | baculoviral IAP repeat containing 3 |
| Synonyms gene | API2 |
| Synonyms gene name | baculoviral IAP repeat-containing 3 |
| Synonyms | cIAP2 hiap-1 MIHC RNF49 MALT2 c-IAP2 |
| Synonyms name | apoptosis inhibitor 2 TNFR2-TRAF signaling complex protein mammalian IAP homolog C inhibitor of apoptosis protein 1 |
| Locus | 11q22, 2 |
| Discovery year | 1998-06-10 |
| GenBank acession | L49432 |
| Entrez gene record | 330 |
| Pubmed identfication | 8552191 8548810 |
| RefSeq identity | NM_001165 |
| Classification | Baculoviral IAP repeat containing Ring finger proteins Caspase recruitment domain containing |
| Havana BLAST/BLAT | OTTHUMG00000167324 |