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CIDEC Antibody

CIDEC Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCIDEC Primary Polyclonal Antibody
Also known asCIDEC PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCIDEC
Specificity Due to the similarity of this protein with CIDEA in Mouse and Rat, there is a chance that this antibody will react with this protein in those two species based on homology, This is a highly specific antibody against CIDEC
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range110-160/238
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CIDEC
Gene ID number63924
Swiss ProtQ96AQ7
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen As mature adipocytes, At focal contact sites between lipid droplets, ID2 and XDH, Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1, May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression, SOCS3, TGFB1, TGFBR1, The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair, When overexpressed in preadipocytes, are quite resistant to apoptotic stimuli, including SOCS1, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets, that express high CIDEC levels, the physiological significance of its role in apoptosis is unclear, thereby restricting lipolysis and favoring storage, Binds to lipid droplets and regulates their enlargement
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CIDE-3, CIDEC, Cell death activator CIDE-3, Cell death-inducing DFFA-like effector protein C, FPLD5, FSP27, Fat-specific protein FSP27 homolog, CIDE3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCIDEC
Short nameCIDEC Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name 45kDa, alpha polypeptide-like effector c (Antibody to), cellular death-inducing Desoxyribonucleic acid fragmentation factor
Alternative techniqueantibodies
Alternative to gene target CIDEC and IDBG-16636 and ENSG00000187288 and 63924, CIDEC and IDBG-644696 and ENSBTAG00000007969 and 534607, Cidec and IDBG-176827 and ENSMUSG00000030278 and 14311, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0034389 and lipid particle organization and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0097194 and execution phase of apoptosis and biological process, molecular_function, nuclei, this GO :0003674 and molecular function and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005811 and lipid particle and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0003674: molecular_function, this GO :0003674: molecular_function, cell death-inducing DFFA-like effector c
Identity 24229
Gene CIDEC
Long gene name cell death inducing DFFA like effector c
Synonyms gene name cell death-inducing DFFA-like effector c
Synonyms CIDE-3 FLJ20871 Fsp27
Locus 3p25, 3
Discovery year 2004-07-26
Entrez gene record 63924
Pubmed identfication 12429024
RefSeq identity NM_022094
Havana BLAST/BLAT OTTHUMG00000128522

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