| Alternative name1 | CKTSF1B1, Cell proliferation-inducing gene 2 protein GREM1, Cysteine knot superfamily 1 BMP antagonist 1, DAN, DAN domain family member 2, DRM, Down-regulated in Mos-transformed cells protein, IHG-2, Increased in high glucose protein 2, Anti-CKTSF1B1 (Gremlin1 |
| Alternative name2 | CKTSF1B1, Cell proliferation-inducing gene 2 protein GREM1, Cysteine knot superfamily 1 BMP antagonist 1, DAN, DAN domain family member 2, DRM, Down-regulated in Mos-transformed cells protein, IHG-2, Increased in high glucose protein 2, CKTSF1B1 (Gremlin1 |
| Alternative name3 | CKTSF1B1, Cell prolifeRattus norvegicusion-inducing gene 2 protein GREM1, Cysteine knot superfamily 1 BMP antagonist 1, DAN, DAN domain family member 2, DRM, Down-regulated in Mos-transformed cells protein, IHG-2, Increased in high glucose protein 2, CKTSF1B1 (Gremlin1 |
| Alternative name4 | CKTSF1B1 |
| Alternative name5 | CKTSF1B1, Cell proliferation-inducing gene 2 protein GREM1, Cysteine knot superfamily 1 BMP antagonist 1, DA, DAN domain family member 2, DRM, Down-regulated in Mos-transformed cells protein, IHG-2, Increased in high glucose protein 2, Anti -CKTSF1B1 (Gremlin1 |
| Other names | N/A |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | N/A |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | IgG |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Rabbit |
| Species reactivity | Rabbit, Rat, Human |
| Specificity and cross-reactivity | Species Crossreactivity: rabbit (IHC), rat (WB), Recognizes human Gremlin 1 |
| Purification method | Affinity Purified by immunoaffinity chromatography |
| Form/Appearance | 0, 0, 5% BSA, Reconstitute with 200ul sterile ddH2O, pH 7, 05% sodium azide, 05% thimerosal, 4, Supplied as a lyophilized powder from PBS |
| Concentration | N/A |
| Storage and shipping | Aliquot to avoid repeated freezing and thawing, For maximum recovery of product, For optimal long term storage, Further dilutions can be made in assay buffer, Reconstitute with sterile ddH2O, Reconstituted product is stable for 12 months productone should be stored at -20 degrees Celsius, Stable for 12 months productone should be stored at -20 degrees Celsius, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Lyophilized powder may be stored productone should be stored at -20 degrees Celsius |
| Tested for: | Immunohistochemistry (IHC), Western Blot (WB) |
| Description | An ELISA is used to detect the expressed protein in biological fluids, MBS Polyclonals_1 produces more antagonist and receptor related products as 1, cDNA genes , saliva, serum, (or region) of , DNA , The antagonist receptor ligand binding will be in contrast with agonist activity, are a , for functional , locus , or , protein, transcript RNA |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target | CKTSF1B1, Cysteine knot superfamily 1 BMP antagonist 1, DAN, DAN domain family member 2, DRM, Down-regulated in Mos-transformed cells protein, IHG-2, Increased in glucose protein 2, proliferation gene 2 protein GREM1, CKTSF1B1 (Gremlin1 |
| Short name | CKTSF1B1, Cell proliferation- 2 protein GREM1, Cysteine knot superfamily 1 BMP antagonist 1, DAN Antibody, DAN domain family member 2, DRM, Down-regulated in Mos-transformed cells protein, IHG-2, Increased in glucose protein 2, CKTSF1B1 (Gremlin1 |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CKTSF1B1, Cysteine knot supergroup 1 BMP antagonist 1, DAN (Antibody to), DAN domain family member 2, DRM, Down-regulated in Mos-transformed cells protein, IHG-2, Increased in high glucose protein 2, cellular expantion-inducing gene 2 protein gremlin 1, CKTSF1B1 (Gremlin1 |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046851 and negative regulation of bone remodeling and biological process this GO :0048018 and receptor a this GO nist activity and molecular function this GO :0048263 and determination of dorsal identity and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051893 and regulation of focal adhesion assembly and biological process this GO :0051973 and positive regulation of telomerase activity and biological process this GO :0060394 and negative regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0060676 and ureteric bud formation and biological process this GO :0061098 and positive regulation of protein tyrosine kinase activity and biological process this GO :0090027 and negative regulation of monocyte chemotaxis and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :0090190 and positive regulation of branching involved in ureteric bud morphogenesis and biological process this GO :0090191 and negative regulation of branching involved in ureteric bud morphogenesis and biological process this GO :0090291 and negative regulation of osteoclast proliferation and biological process this GO :1900086 and positive regulation of peptidyl-tyrosine autophosphorylation and biological process this GO :1900155 and negative regulation of bone trabecula formation and biological process this GO :1900158 and negative regulation of bone mineralization involved in bone maturation and biological process this GO :2000273 and positive regulation of receptor activity and biological process this GO :2000727 and positive regulation of cardiac muscle cell differentiation and biological process, Extracellular, GREM1 and IDBG-5193 and ENSG00000166923 and 26585, GREM1 and IDBG-648566 and ENSBTAG00000046604 and 539079, Grem1 and IDBG-197200 and ENSMUSG00000074934 and 23892, receptor a this GO nist activity, this GO :0000902 and cell morphogenesis and biological process this GO :0001525 and angiogenesis and biological process this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0002042 and cell migration involved in sprouting angiogenesis and biological process this GO :0002092 and positive regulation of receptor internalization and biological process this GO :0002689 and negative regulation of leukocyte chemotaxis and biological process this GO :0003257 and positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation and biological process this GO :0003337 and mesenchymal to epithelial transition involved in metanephros morphogenesis and biological process this GO :0005125 and cytokine activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007171 and activation of transmembrane receptor protein tyrosine kinase activity and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0009954 and proximal/distal pattern formation and biological process this GO :0009986 and cell surface and cellular component this GO :0010717 and regulation of epithelial to mesenchymal transition and biological process this GO :0016015 and morphogen activity and molecular function this GO :0030199 and collagen fibril organization and biological process this GO :0030297 and transmembrane receptor protein tyrosine kinase activator activity and molecular function this GO :0030308 and negative regulation of cell growth and biological process this GO :0030326 and embryonic limb morphogenesis and biological process this GO :0030502 and negative regulation of bone mineralization and biological process this GO :0030514 and negative regulation of BMP signaling pathway and biological process this GO :0033689 and negative regulation of osteoblast proliferation and biological process this GO :0036122 and BMP binding and molecular function this GO :0042346 and positive regulation of NF-kappaB import into nucleus and biological process this GO :0043184 and vascular endothelial growth factor receptor 2 binding and molecular function this GO :0043542 and endothelial cell migration and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0045892 and negative regulation of transcription, this GO :0005125: cytokine activity, this GO :0005125: cytokine activity and also this GO :0005515: protein binding and also this GO :0016015: morphogen activity and also this GO :0030297: transmembrane receptor protein tyrosine kinase activator activity and also this GO :0036122: BMP binding and also this GO :0043184: vascular endothelial growth factor receptor 2 binding and also this GO :0048018: receptor a this GO nist activity, this GO :0005515: protein binding, this GO :0016015: morphogen activity, this GO :0030297: transmembrane receptor protein tyrosine kinase activator activity, this GO :0036122: BMP binding, this GO :0043184: vascular endothelial growth factor receptor 2 binding, this GO :0048018: receptor a this GO nist activity, gremlin 1 |
| Identity | 2001 |
| Gene | GREM1 |
| Long gene name | DAN family BMP antagonist , gremlin 1 |
| Synonyms gene | CKTSF1B1 CRAC1 |
| Synonyms gene name | BMP antagonist 1 gremlin 1, cysteine knot superfamily, cysteine knot superfamily 1, homolog (Xenopus laevis) gremlin 1 colorectal adenoma and carcinoma 1 |
| Synonyms | DRM gremlin DAND2 HMPS |
| Locus | 15q13, 3 |
| Discovery year | 1999-12-02 |
| Entrez gene record | 26585 |
| Pubmed identfication | 9660951 10026205 22561515 27385727 |
| RefSeq identity | NM_013372 |
| Classification | DAN family |
| Havana BLAST/BLAT | OTTHUMG00000129319 |
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