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Claudin 14 Antibody, ALEXA FLUOR 350

Claudin 14 Antibody, ALEXA FLUOR 350 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 350 Conjugated, Claudin 14 Polyclonal Antibody
Also known asAnti-Claudin 14 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenClaudin 14
SpecificityThis is a highly specific antibody against Claudin 14
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Claudin 14
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions, Claudin-14 is a multi-pass membrane protein that is expressed in liver, Claudins, Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues, Defects in the gene encoding claudin-14 are the cause of non-syndromic sensorineural deafness autosomal recessive type 29 (DFNB29), Occludin and Junction adhesion molecules, These proteins are important structural and functional components of tight junctions in paracellular transport, Three classes of proteins are known to localize to tight junctions, a form of hearing loss resulting from damage to either nerve pathways or neural receptors of the inner ear, including the claudins, kidney and ear, make up tight junction strands, which consist of four transmembrane domains and two extracellular loops, The Claudin superfamily consists of many structurally related proteins in humans
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetClaudin 14
Short nameClaudin 14 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, Claudin 14 (Antibody to)
Alternative techniqueantibodies
Identity 2035
Gene CLDN14
Long gene name claudin 14
Synonyms gene DFNB29
Locus 21q22, 13
Discovery year 1999-11-26
GenBank acession AJ132445
Entrez gene record 23562
Pubmed identfication 11163249
RefSeq identity NM_144492
Classification Claudins Deafness associated genes
Havana BLAST/BLAT OTTHUMG00000086638
Locus Specific Databases Hereditary Hearing Loss Homepage

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