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Claudin 2 Antibody, FITC Conjugated

Claudin 2 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, Claudin 2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenClaudin 2
SpecificityThis is a highly specific antibody against Claudin 2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Claudin 2
Gene ID number9075
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Able to form homopolymers of heteropolymers with other claudin family members, Claudin-2, Overexpression of claudin-2 is associated with a variety of diseases, The gene encoding claudin-2 maps to human chromosome X, also known as CLDN2 or SP82, claudin-2 plays an essential role in mediating calcium-independent cell-adhesion activity that is necessary for tight junction-specific obliteration of the intercellular space, colorectal cancer, further affirming the importance of claudin-2 in cell adhesion, gastrointestinal carcinomas and inflammatory bowel disease, including lung cancer, is a 230 amino acid multi-pass membrane protein that localizes to the cell junctions and belongs to the claudin superfamily, which contains nearly 153 million base pairs and houses over 1, 000 genes, The claudin superfamily consists of structurally related proteins that are important structural and functional components of tight junctions
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms CLD2_HUMAN, CLDN 2, CLDN2, Claudin2, OTTHUMP00000023793, SP 82, SP82, Claudin-2
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetClaudin 2 Conjugated
Short name FITC Conjugated, Claudin 2 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, Claudin 2 (Antibody to)
Alternative techniqueantibodies

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