Name : CLEC4E Antibody
Supplier : NJS POLY
Price :320
SKU : GEN9916662761
| Category | Antibody |
| Concentration | 05% sodium azide, 1 mg/ml BSA (US sourced) and 0, 5 mg/ml in 1X PBS with 0 |
| Form | Purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | CLEC4E |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | WB |
| Recommended dilutions | Western blot: 2-5ug/ml |
| Notes | CLEC4E antibody titration may be required for optimal results, Provided assay concentrations are suggestions only |
| Added buffer | pH 7, 1X Phosphate Buffered Saline (PBS), 4 |
| Intented use | This CLEC4E antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID # | 26253 |
| Purity | Purified by protein A Affinity Chromatography |
| Description | 130kDa), CLEC4E, CLEC4E senses this and interacts with the ITAM-containing adaptor protein FcR&, Dead cells release SAP130 (Sin3A-Associated Protein, It is a receptor for both non-self (fungi and mycobacteria), MIP-2 and IL-6, a small nuclear ribonucleoprotein component, activates the production of inflammatory cytokines such as TNFa, also called Mincle (Macrophage-inducible C-type lectin), and self (damaged cells) ligands, and via Syk and CARD9 signaling, is found on the surface of activated macrophages and phagocytes, #947, CLEC4 is a member of the C-type lectin family of proteins that plays a role in inflammatory and immune response |
| Immunogen | A recombinant protein fragment from the C-terminal portion of human CLEC4E was used as the immunogen for this antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CLEC4E antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | CLEC4E |
| Short name | CLEC4E Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CLEC4E (Antibody to) |
| Alternative technique | antibodies |
| Identity | 14555 |
| Gene | CLEC4E |
| Long gene name | C-type lectin domain family 4 member E |
| Synonyms gene | CLECSF9 |
| Synonyms gene name | C-type (calcium dependent, carbohydrate-recognition domain) lectin, member E , superfamily member 9 C-type lectin domain family 4 |
| Synonyms | mincle |
| Synonyms name | Macrophage-inducible C-type lectin |
| Locus | 12p13, 31 |
| Discovery year | 2001-02-01 |
| GenBank acession | AB024718 |
| Entrez gene record | 26253 |
| Pubmed identfication | 10528209 |
| RefSeq identity | NM_014358 |
| Classification | C-type lectin domain family |
| Havana BLAST/BLAT | OTTHUMG00000168675 |