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CLEC4E Antibody

CLEC4E Antibody size: 0.1mg 320

Supplier NJS POLY
Price 320
Size 0.1mg
CategoryAntibody
Concentration05% sodium azide, 1 mg/ml BSA (US sourced) and 0, 5 mg/ml in 1X PBS with 0
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCLEC4E
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutionsWestern blot: 2-5ug/ml
Notes CLEC4E antibody titration may be required for optimal results, Provided assay concentrations are suggestions only
Added buffer pH 7, 1X Phosphate Buffered Saline (PBS), 4
Intented useThis CLEC4E antibodyis to be used only for research purposes and not for diagnostics
Gene ID #26253
PurityPurified by protein A Affinity Chromatography
Description 130kDa), CLEC4E, CLEC4E senses this and interacts with the ITAM-containing adaptor protein FcR&, Dead cells release SAP130 (Sin3A-Associated Protein, It is a receptor for both non-self (fungi and mycobacteria), MIP-2 and IL-6, a small nuclear ribonucleoprotein component, activates the production of inflammatory cytokines such as TNFa, also called Mincle (Macrophage-inducible C-type lectin), and self (damaged cells) ligands, and via Syk and CARD9 signaling, is found on the surface of activated macrophages and phagocytes, #947, CLEC4 is a member of the C-type lectin family of proteins that plays a role in inflammatory and immune response
ImmunogenA recombinant protein fragment from the C-terminal portion of human CLEC4E was used as the immunogen for this antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CLEC4E antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCLEC4E
Short nameCLEC4E Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCLEC4E (Antibody to)
Alternative techniqueantibodies
Identity 14555
Gene CLEC4E
Long gene name C-type lectin domain family 4 member E
Synonyms gene CLECSF9
Synonyms gene name C-type (calcium dependent, carbohydrate-recognition domain) lectin, member E , superfamily member 9 C-type lectin domain family 4
Synonyms mincle
Synonyms name Macrophage-inducible C-type lectin
Locus 12p13, 31
Discovery year 2001-02-01
GenBank acession AB024718
Entrez gene record 26253
Pubmed identfication 10528209
RefSeq identity NM_014358
Classification C-type lectin domain family
Havana BLAST/BLAT OTTHUMG00000168675

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