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CNGB3 Antibody

CNGB3 Antibody size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH7, with 0, 02% sodium azide, 3, 5 mg/ml in 1X TBS, 5% BSA (US sourced) and 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCNGB3
Host animalGoat (Capra aegagrus hircus)
ClonalityPolyclonal (goat origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA (peptide), IHC-P
Recommended dilutionsELISA (peptide) LOD: 1:8000, IHC (FFPE): 2-4ug/ml
NotesOptimal dilution of the CNGB3 antibody should be determined by the researcher
Intented useThis CNGB3 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9NQW8
PurityAntigen affinity
Description Cyclic nucleotide-gated cation channel beta-3 can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors, Essential for the generation of light-evoked electrical responses in the red-, Induced a flickering channel gating, [UniProt], green- and blue sensitive cones, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the channel when coexpressed with CNGA3 (By similarity), weakened the outward rectification in the presence of extracellular calcium, Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger
ImmunogenAmino acids ESDDKPTEHYYR were used as the immunogen for this CNGB3 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot and store the CNGB3 antibody at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCNGB3
Short nameCNGB3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCNGB3 (Antibody to)
Alternative techniqueantibodies
Identity 2153
Gene CNGB3
Long gene name cyclic nucleotide gated channel beta 3
Synonyms gene ACHM3 ACHM1 RMCH
Synonyms gene name achromatopsia (rod monochromacy) 3 achromatopsia (rod monochromacy) 1
Locus 8q21, 3
Discovery year 2000-07-12
GenBank acession AF228520
Entrez gene record 54714
Pubmed identfication 10888875 10958649 16382102
RefSeq identity NM_019098
Classification Cyclic nucleotide gated channels
Havana BLAST/BLAT OTTHUMG00000163738

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