Name : Complement C4 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN3450582860
| Long name | Complement C4 Primary Polyclonal Antibody |
| Also known as | Complement C4 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Complement C4 |
| Specificity | This is a highly specific antibody against Complement C4 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 70-120/1744 |
| Subcellular location | Secreted |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Complement C4 |
| Gene ID number | 720721 |
| Swiss Prot | P0C0L4 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, C4a anaphylatoxin is a mediator of local inflammatory process, Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes, Derived from proteolytic degradation of complement C4, It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens, Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Acidic complement C4, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2, C4A, C4A2, C4A3, C4A4, C4A6, C4AD, C4B1, C4B12, C4B2, C4B3, C4B5, C4BD, C4B_2, C4F, C4S, CH, CO4, CPAMD2, CPAMD3, Complement C4-A, RG, C4 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Complement C4 |
| Short name | Complement C4 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Complement C4 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 1323 |
| Gene | C4A |
| Long gene name | complement C4A (Rodgers blood group) |
| Synonyms gene name | complement component 4A complement component 4A (Rodgers blood group) |
| Synonyms | CPAMD2 C4S CO4 C4 C4A3 C4A2 C4A4 C4A6 C4B RG |
| Locus | 6p21, 33 |
| Discovery year | 2001-06-22 |
| GenBank acession | L26261 M14823 X77491 AY224378 |
| Entrez gene record | 720 |
| RefSeq identity | NM_007293 |
| Classification | Complement system Blood group antigens C3 and PZP like, alpha-2-macroglobulin domain containing |
| Havana BLAST/BLAT | OTTHUMG00000031186 |
| Locus Specific Databases | LRG_137 |