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COX 1 Antibody

COX 1 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCOX 1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the COX 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis COX 1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P23219
PurityAntigen affinity
Description By analysis of a human/hamster somatic hybrid DNA panel, Funk et al, Gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration, Human COX 1 exhibited 91% amino acid identity with the sheep enzyme, The gene was approximately 40 kb long, There were 599 amino acid residues with a calculated molecular mass of approximately 68 kD, also known as Prostaglandin-endoperoxide synthase (PTGS1) or mitochondrial cytochrome c oxidase subunit 1, is the key enzyme in prostaglandin biosynthesis, with 11 protein-coding exons, (1991) demonstrated that the gene maps to chromosome 9, Cyclooxygenase 1
ImmunogenAn amino acid sequence from the N-terminus of human COX1 (CCYYPCQHQGICVRFGLD) was used as the immunogen for this COX 1 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the COX 1 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCOX 1
Short nameCOX 1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCOX 1 (Antibody to)
Alternative techniqueantibodies
Identity 2294
Gene COX8A
Long gene name cytochrome c oxidase subunit 8A
Synonyms gene COX8
Synonyms gene name cytochrome c oxidase subunit VIII cytochrome c oxidase subunit VIIIA (ubiquitous)
Synonyms COX8-2 COX8L VIII-L COX VIII
Locus 11q13, 1
Discovery year 1989-06-30
GenBank acession J04823
Entrez gene record 1351
Pubmed identfication 2543673 2847943
RefSeq identity NM_004074
Classification Mitochondrial complex IV: cytochrome c oxidase subunits
Havana BLAST/BLAT OTTHUMG00000167785

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