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CREB-1(Ser142) Antibody

CREB-1(Ser142) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCREB-1(Ser142) Primary Polyclonal Antibody
Also known asCREB-1(Ser142) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCREB-1Ser142
SpecificityThis is a highly specific antibody against CREB-1Ser142
Modification(s)Phosphorylation
Modification site(s)Ser142
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human CREB-1 around the phosphorylation site of Ser142 [DL(p-S)SD]
Gene ID number1385
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen ATF-1, Although each of the ATF/CREB proteins bind CREs in their homodimeric form, CREB-2, It has recentlybeen shown that protein kinase A-mediated CREB phosphorylation results in its binding to a 265kDa nuclear protein designated CBP (CREB-binding protein), TGACCTCA, The best characterized members of this gene family include CREB-1, both within the ATF/CREB family and with members of the AP-1 transcription factor family, in cerain instances they also bind as heterodimers, these transcription factors share highly-related COOH terminal leucine zipper demerization and basic DNA bindings but are highly divergent in their amino terminal domains, which may reprecent a CREB co-activator, ATF-2, ATF-3and ATF-4, The ATF/CREB family consists of transcription factors that function through binding to the cAMP responsive element (CRE) palindromic octanucleotide
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CREB, CREB 1, CREB1, CREB1, MGC9284, Transactivator protein, cAMP response element binding protein, cAMP responsive element binding protein 1, Active transcription factor CREB
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCREB-1(Ser142)
Short nameCREB-1(Ser142) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCREB-1(Ser142) (Antibody to)
Alternative techniqueantibodies

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