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CRLF2 Antibody

CRLF2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCRLF2 Primary Polyclonal Antibody
Also known asCRLF2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCRLF2
SpecificityThis is a highly specific antibody against CRLF2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CRLF2
Gene ID number64109
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Expression has also been reported in heart, Ligand receptor interactions haves been implicated in the development of the hematopoietic system, STAT3 and STAT5 to stimulate cell proliferation, TSLP binding to the heterodimeric functional receptor (TSLPR and IL7R) activates JAK2, TSLPR has a predicted molecular weight approximately 41 kD, The TSLP R contains a WSXWS motif required for proper protein folding and a box1 motif important for association with the JAKs, The TSLPR is expressed preferentially in myeloid cells including dendritic cells and activated monocytes, and is weakly expressed in T cells, and kidney tissues, and the maintenance and polarization of human Th2 memory T cells in allergic diseases, and two further isoforms have been reported that are produced by alternative splicing, dendritic cell maturation, skeletal muscle, TSLPR is a type I membrane receptor that forms a functional heterodimeric complex with IL7R to bind TSLP
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CRL 2, CRL2, CRLF 2, CRLF2, CRLF2Y, Cytokine receptor CRL2 precusor, Cytokine receptor like 2, Cytokine receptor like factor 2, Cytokine receptor like factor 2 precursor, IL XR, ILXR, TSLP receptor, TSLPR, Thymic stromal derived lymphopoietin receptor, Thymic stromal lymphopoietin protein receptor, Thymic stromal lymphopoietin receptor, TSLPR
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCRLF2
Short nameCRLF2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namecytokine receptor-like factor 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CRLF2 and IDBG-39359 and ENSG00000205755 and 64109, CRLF2 and IDBG-645338 and ENSBTAG00000020242 and 529792, Crlf2 and IDBG-188983 and ENSMUSG00000033467 and 57914, Extracellular, protein binding, this GO :0002380 and immunoglobulin secretion involved in immune response and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0035745 and T-helper 2 cell cytokine production and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, cytokine receptor-like factor 2
Identity 14281
Gene CRLF2
Long gene name cytokine receptor-like factor 2
Synonyms CRL2 TSLPR
Locus Xp22, 3 , 3 and Yp11
Discovery year 2001-02-06
GenBank acession AF142570
Entrez gene record 64109
Pubmed identfication 11237741 11474172
RefSeq identity NM_022148
Classification Fibronectin type III domain containing Pseudoautosomal region 1
Havana BLAST/BLAT OTTHUMG00000067432

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