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CSEN Antibody

CSEN Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCSEN
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Notes Titration of the CSEN antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis CSEN antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9Y2W7
PurityAntigen affinity
Description Calsenilin functions as a calcium-regulated transcriptional repressor, It has been shown to interact with PSEN1 and PSEN2, KCNIP3-regulated genes have a critical function in Ig subclass production and proliferation in B lymphocytes, The KCNIP3 gene encodes a member of the family of voltage-gated potassium(Kv) channel-interacting proteins, and immune cells, and interacts with presenilins, testis, thymus, thyroid gland, which belong to the neuronal calcium sensor family of proteins, Calsenilin (CSEN) is a calcium-dependent transcriptional repressor that is highly expressed in central nervous system
ImmunogenAn amino acid sequence from the N-terminus of human Calsenilin (MQPAKEVTKASDGSLL) was used as the immunogen for this CSEN antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CSEN antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCSEN
Short nameCSEN Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCSEN (Antibody to)
Alternative techniqueantibodies
Identity 15523
Gene KCNIP3
Long gene name potassium voltage-gated channel interacting protein 3
Synonyms gene CSEN
Synonyms gene name EF hand transcription factor Kv channel interacting protein 3, calsenilin, calsenilin , presenilin-binding protein
Synonyms DREAM KCHIP3
Synonyms name calsenilin
Locus 2q11, 1
Discovery year 2001-05-24
GenBank acession AF199599
Entrez gene record 30818
Pubmed identfication 9771752 10078534
RefSeq identity NM_013434
Classification Potassium voltage-gated channel regulatory subunits EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000130392

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