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CSN1 Antibody

CSN1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCSN1 Primary Polyclonal Antibody
Also known asCSN1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCSN1
SpecificityThis is a highly specific antibody against CSN1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range324-370/491
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CSN1
Gene ID number2873
Swiss ProtQ13098
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CSA or DDB2, CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, ITPK1 and IRF8/ICSBP, IkappaBalpha/NFKBIA, Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction, The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, The complex is also involved in phosphorylation of p53/TP53, a complex involved in various cellular and developmental processes, c-jun/JUN, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, possibly via its association with CK2 and PKD kinases, respectively, Essential component of the COP9 signalosome complex (CSN)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names COP9 signalosome complex subunit 1, COPS1, G protein pathway suppressor 1, GPS-1, GPS1, JAB1-containing signalosome subunit 1, Protein MFH, SGN1, Signalosome subunit 1, CSN1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCSN1
Short nameCSN1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCSN1 (Antibody to)
Alternative techniqueantibodies
Identity 4549
Gene GPS1
Long gene name G protein pathway suppressor 1
Synonyms COPS1 CSN1
Synonyms name COP9 signalosome subunit 1
Locus 17q25, 3
Discovery year 1997-10-10
Entrez gene record 2873
Pubmed identfication 9535219
RefSeq identity NM_212492
Classification COP9 signalosome
Havana BLAST/BLAT OTTHUMG00000178484

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