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CSN7b Antibody

CSN7b Antibody size: 0.1ml 263

Price 263
Size 0.1ml
Long nameCSN7b Primary Polyclonal Antibody
Also known asCSN7b PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCSN7b
SpecificityThis is a highly specific antibody against CSN7b
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CSN7b
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen COPS7a) or CSN7b (COP7b) and CSN8 (COP8), CSN2 (COPS2), CSN3, CSN3 (COPS3), CSN4, CSN4 (COPS4), CSN5, CSN5 (COPS5), CSN6, CSN6 (COP6), CSN7 is phosphorylated by CK2 and is composed of two subunits, CSN7a (COPS7, CSN7a contains a PCI (Proteasome CSN9 initiation factor 3) region, CSN7b contains only a PCI region and is predicted to interact with INT6, CSN8, I&, It is also involved in the phosphorylation of p53, The CSN complex acts as a regulator for the ubiquitin conjugation pathway by mediating the deneddylation of the SCF-type E3 ligase complexes, The complex is made up of several widely expressed proteins: CSN1 (COPS1), a and b, and GPS1, and IRF-8, and c-Jun protects and promotes degradation by the Ubl system, as well as CSN-dependent phosphorylation of p53, as well as a coiled-coil region and is predicted to interact with CSN2, c-Jun, which leads to a decrease in ubiquitin ligase activity of SCF-complexes, #730, B&, The COP9 signalosome (CSN) complex is involved in several different developmental and cellular processes, aring
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names COP9 Constitutive Photomorphogenic Homolog Subunit 7b, COP9 Signalasome Subunit 7b, COP9 signalosome complex subunit 7b, COPS7B, CSN7B_HUMAN, JAB1 Containing Signalosome Subunit 7b, JAB1-containing signalosome subunit 7b, SGN7b, Signalosome subunit 7b, COP9 Complex Homolog Subunit 7b
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCSN7b
Short nameCSN7b Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCSN7b (Antibody to)
Alternative techniqueantibodies
Identity 16760
Gene COPS7B
Long gene name COP9 signalosome subunit 7B
Synonyms gene name Arabidopsis, COP9 (constitutive photomorphogenic, homolog) subunit 7B COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis)
Synonyms CSN7B
Locus 2q37, 1
Discovery year 2001-10-03
GenBank acession AK022674
Entrez gene record 64708
Pubmed identfication 9707402
RefSeq identity NM_022730
Classification COP9 signalosome
Havana BLAST/BLAT OTTHUMG00000133228

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