Name : CstF64(Ser498) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN5730333762
| Long name | CstF64(Ser498) Primary Polyclonal Antibody |
| Also known as | CstF64(Ser498) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | CstF64 Ser498 |
| Specificity | This is a highly specific antibody against CstF64 Ser498 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser498 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human CstF64 around the phosphorylation site of Ser498 |
| Gene ID number | 1478 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | CstF-64 contains an RNA binding domain and is responsible for the RNA binding activity of CstF, CstF-64 is expressed in all somatic cells and in pre- and postmeiotic, However, The first step, The gene encoding CstF-64 (designated CSTF2) maps to the X chromosome, The increase in CstF-64 concentration during B cell activation switches IgM heavy chain mRNA expression from membrane-bound to secreted forms, a heterotrimer that is composed of three distinct subunits, a large variant of CstF-64, and promotes the germ cell pattern of polyadenylation, but not meiotic, called t CstF-64, endonucleolytic cleavage of polyadenylation substrates, germ cells, is abundantly expressed in meiotic and postmeiotic cells in the testis and to a lesser extent in the brain, requires CstF (cleavage stimulation factor), suggesting that CstF-64 plays a key role in regulating IgM heavy chain expression during B cell differentiation, whereas t CstF-64 is encoded by an autosomal gene, Polyadenylation of mRNA precursors is a two-step reaction that requires multiple protein factors |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CF1 64 kDa subunit, CSTF 64 kDa subunit, CSTF2T, CSTF2_HUMAN, Cleavage stimulation factor 64 kDa subunit, CstF64 S498, CstF64 Ser498, KIAA0689, TauCstF64, p-CstF-64 S498, tau variant, tau variant, tau variant, p-CstF-64 Ser498 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | CstF64(Ser498) |
| Short name | CstF64(Ser498) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CstF64(Ser498) (Antibody to) |
| Alternative technique | antibodies |