Name : CXCL12 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN2384550277
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | CXCL12 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, WB, IHC |
| Recommended dilutions | IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the CXCL12 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This CXCL12 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P48061 |
| Purity | Antigen affinity |
| Description | Multiple transcript variants encoding different isoforms have been found for this gene, Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections, This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer, This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family |
| Immunogen | A portion of amino acids 64-92 from the human protein was used as the immunogen for this CXCL12 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CXCL12 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | CXCL12 |
| Short name | CXCL12 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | chemokine (C-X-C motif) ligand 12 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | CXCL12 and IDBG-632037 and ENSBTAG00000005077 and 613811, CXCL12 and IDBG-71595 and ENSG00000107562 and 6387, CXCR chemokine receptor binding, Cxcl12 and IDBG-180998 and ENSMUSG00000061353 and 20315, Extracellular, IRH and PBSF and SCYB12 and SDF1 and TLSF and TPAR1, this GO :0001569 and patterning of blood vessels and biological process this GO :0001666 and response to hypoxia and biological process this GO :0001667 and ameboidal cell migration and biological process this GO :0001764 and neuron migration and biological process this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0005102 and receptor binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006935 and chemotaxis and biological process this GO :0006955 and immune response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007281 and germ cell development and biological process this GO :0007420 and brain development and biological process this GO :0008009 and chemokine activity and molecular function this GO :0008015 and blood circulation and biological process this GO :0008045 and motor neuron axon guidance and biological process this GO :0008064 and regulation of actin polymerization or depolymerization and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008344 and adult locomotory behavior and biological process this GO :0008354 and germ cell migration and biological process this GO :0009314 and response to radiation and biological process this GO :0009408 and response to heat and biological process this GO :0009612 and response to mechanical stimulus and biological process this GO :0009615 and response to virus and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0022029 and telencephalon cell migration and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0031100 and organ regeneration and biological process this GO :0033603 and positive regulation of dopamine secretion and biological process this GO :0042098 and T cell proliferation and biological process this GO :0042379 and chemokine receptor binding and molecular function this GO :0043434 and response to peptide hormone and biological process this GO :0045087 and innate immune response and biological process this GO :0045236 and CXCR chemokine receptor binding and molecular function this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0048842 and positive regulation of axon extension involved in axon guidance and biological process this GO :0050930 and induction of positive chemotaxis and biological process this GO :0051924 and regulation of calcium ion transport and biological process this GO :0060326 and cell chemotaxis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070098 and chemokine-mediated signaling pathway and biological process this GO :0090026 and positive regulation of monocyte chemotaxis and biological process this GO :0090280 and positive regulation of calcium ion import and biological process this GO :1902230 and negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :2000107 and negative regulation of leukocyte apoptotic process and biological process this GO :2000406 and positive regulation of T cell migration and biological process, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0008009: chemokine activity and also this GO :0008083: growth factor activity and also this GO :0042379: chemokine receptor binding and also this GO :0045236: CXCR chemokine receptor binding, this GO :0008009: chemokine activity, this GO :0008083: growth factor activity, this GO :0042379: chemokine receptor binding, this GO :0045236: CXCR chemokine receptor binding, chemokine (C-X-C motif) ligand 12 |
| Identity | 10672 |
| Gene | CXCL12 |
| Long gene name | C-X-C motif chemokine ligand 12 |
| Synonyms gene | SDF1A SDF1B SDF1 |
| Synonyms gene name | stromal cell-derived factor 1 chemokine (C-X-C motif) ligand 12 |
| Synonyms | SCYB12 SDF-1a SDF-1b PBSF TLSF-a TLSF-b TPAR1 |
| Locus | 10q11, 21 |
| Discovery year | 1994-11-30 |
| GenBank acession | L36033 |
| Entrez gene record | 6387 |
| Pubmed identfication | 7490086 |
| RefSeq identity | NM_000609 |
| Classification | Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT | OTTHUMG00000018054 |