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CXCR6 Antibody

CXCR6 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenCXCR6
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the CXCR6 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis CXCR6 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #O00574
PurityAntigen affinity
Description By Southern blot analysis of genomic DNA and somatic cell hybrid analysis, Kim et al, Liao et al, Matloubian et al, The authors concluded that CXCL16 and CXCR6 most likely function in interactions between dendritic cells and T cells and in regulating T-cell migration in the splenic red pulp, also known as STRL33 and Bonzo, is a protein that in humans is encoded by the CXCR6 gene, (1997) mapped the single-copy gene to chromosome 3, (2000) found that human and mouse cells expressing the protein showed a strong chemotactic response to CXCL16 but not to other chemokines, (2001) concluded that the proteinb may be important in the trafficking of effector T cells mediating type-1 inflammation, Chemokine CXC Motif Receptor 6
ImmunogenAn amino acid sequence from the C-terminus of human Chemokine CXC Motif Receptor 6 (EDNSKTFSASHNVEATSMFQL) was used as the immunogen for this CXCR6 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CXCR6 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetCXCR6
Short nameCXCR6 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namechemokine (C-X-C motif) receptor 6 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BONZO and CD186 and STRL33 and TYMSTR, C-X-C chemokine receptor activity, CXCR6 and IDBG-29993 and ENSG00000172215 and 10663, CXCR6 and IDBG-646261 and ENSBTAG00000015708 and 506807, Cxcr6 and IDBG-206490 and ENSMUSG00000048521 and 80901, Plasma membranes, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0015026 and coreceptor activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016494 and C-X-C chemokine receptor activity and molecular function this GO :0019079 and viral genome replication and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004930: G-protein coupled receptor activity, this GO :0004930: G-protein coupled receptor activity and also this GO :0015026: coreceptor activity and also this GO :0016494: C-X-C chemokine receptor activity, this GO :0015026: coreceptor activity, this GO :0016494: C-X-C chemokine receptor activity, chemokine (C-X-C motif) receptor 6
Identity 16647
Gene CXCR6
Long gene name C-X-C motif chemokine receptor 6
Synonyms gene name chemokine (C-X-C motif) receptor 6
Synonyms TYMSTR STRL33 BONZO CD186
Locus 3p21, 31
Discovery year 2002-08-23
GenBank acession AF007545
Entrez gene record 10663
Pubmed identfication 9166430 9230441
Classification CD molecules C-X-C motif chemokine receptors
Havana BLAST/BLAT OTTHUMG00000133448

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