Filters

Cyclin B1

Cyclin B1 size: 100ug 354

Supplier MBS MONO
Price 354
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCyclin B1
Other names G2/mitotic-specific cyclin B1, G2/mitotic-specific cyclin-B1, G2/mitotic-specific cyclin-B1, N/A, cyclin B1, G2/mitotic-specific cyclin-B1
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCCNB1
Gene name synonimsN/A
Other gene names CCNB, CCNB, CCNB1, CCNB1
ClonalityMonoclonal
Immunoglobulin isotype kappa, IgG1
Clone1, V92
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, Hamster, Mouse (Mus musculus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity In mammals, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, So, The inactive cyclin B-p34cdc2 complex continues to accumulate in the cytoplasm until the completion of DNA synthesis, This degradation process is ubiquitin-dependent and is necessary for the cell to exit mitosis, This maintains the inactive state until the end of G2-phase, This mitotic kinase complex remains active until the metaphase/anaphase transition when cyclin B is degraded, This particular antibody might cross react with speacies outside of the listed ones, a specific protein phosphatase, cyclin B associates with inactive p34cdc2, cyclin B-p34cdc2 plays a critical role in G2 to M transition, dephosphorylates aa 14Thr and 15Tyr of p34cdc2 rendering the complex active at the G2/M boundary, identified as cyclin B1, when Cdc25, which facilitates phosphorylation of p34cdc2 at aa 14Thr and 15Tyr, It recognizes a protein of 55-62kDa
Purification methodN/A
Form/AppearanceN/A
ConcentrationN/A
Storage and shipping Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C
Tested applications: Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), ELISA (EIA)
Gene targetCyclin B1
Short nameCyclin B1
Alternative nameCyclin B1
Identity 1579
Gene CCNB1
Long gene name cyclin B1
Synonyms gene CCNB
Synonyms name G2/mitotic-specific cyclin B1
Locus 5q13, 2
Discovery year 1991-12-10
GenBank acession U22364
Entrez gene record 891
Pubmed identfication 1386342
RefSeq identity NM_031966
Classification Cyclins
Havana BLAST/BLAT OTTHUMG00000097817

Similar products

Subscribe to our Newsletter