| Alternative name 1 | C-terminal, Clone: M3A7, IH/IP/WB, Mab anti-Human, NO Mouse or Dogfish Shark, NO paraffin, Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) |
| Alternative name 2 | C-terminal, Clone: M3A7, IH/IP/WB, Mab antibody-Human, NO Mouse or Dogfish Shark, NO paraffin, Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) |
| Alternative name 3 | C-terminal, Clone: M3A7, IH/IP/WB, Mab antibody-Homo sapiens, NO Mus musculus or Caninefish Shark, NO paraffin, Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) |
| Alternative name 4 | anti-Cystic Fibrosis Transmembrane Conductance Regulator CFTR C-terminal Clone: M3A7 NO or fish Shark NO IP/ |
| Alternative name 5 | Cystic Fibrosis Transmembrane Conductance Regulator CFTR C-terminal Clone: M3A7 NO or fish Shark NO IP/ |
| Clonality | Monoclonal Antibody |
| Description | Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling | Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory | For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| French translation | anticorps |
| Gene target | IH/IP/, M3A7, Monoclonal NO Dogfish Shark, NO paraffin, Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) |
| Short name | Clone: M3A7, IH/IP/, Mouse Monoclonal antibody- NO Mouse Dogfish Shark, NO paraffin, Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) C-terminal |
| Technique | Monoclonals or monoclonal antibodies, mouses, paraffin |
| Species | Humans, Mouses, Mouse |
| Alternative name | C-terminal, IH/IP/Western Blot, Mouse monoclonal (Antibody to)-H, NO Mouse and Dogfish Shark, NO paraffin, clonality: M3A7, member 7)), sapiens, Cystic Fibrosis Transmembrane Conductance Regulator (cystic fibrosis transmembrane conductance regulator (adenosine triphosphate-binding cassette sub-family C |
| Alternative technique | murine |
| Alternative to gene target | ABC35 and ABCC7 and CF and CFTR/MRP and dJ760C5, ATPase activity, CFTR and IDBG-37713 and ENSG00000001626 and 1080, CFTR and IDBG-632747 and ENSBTAG00000006589 and 281067, Cell surfaces, Cftr and IDBG-129229 and ENSMUSG00000041301 and 12638, coupled to transmembrane movement of substances, coupled to transmembrane movement of substances, coupled to transmembrane movement of substances and molecular function this GO :0043234 and protein complex and cellular component this GO :0043434 and response to peptide hormone and biological process this GO :0043627 and response to estrogen and biological process this GO :0045087 and innate immune response and biological process this GO :0045909 and positive regulation of vasodilation and biological process this GO :0048240 and sperm capacitation and biological process this GO :0051454 and intracellular pH elevation and biological process this GO :0055085 and transmembrane transport and biological process this GO :0060081 and membrane hyperpolarization and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071320 and cellular response to cAMP and biological process this GO :1902476 and chloride transmembrane transport and biological process this GO :1902943 and positive regulation of voltage-gated chloride channel activity and biological process, member 7), this GO :0005224 and ATP-binding and phosphorylation-dependent chloride channel activity and molecular function this GO :0005254 and chloride channel activity and molecular function this GO :0005260 and channel-conductance-controlling ATPase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005769 and early endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005902 and microvillus and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006695 and cholesterol biosynthetic process and biological process this GO :0006810 and transport and biological process this GO :0006811 and ion transport and biological process this GO :0006821 and chloride transport and biological process this GO :0006833 and water transport and biological process this GO :0007585 and respiratory gaseous exchange and biological process this GO :0009986 and cell surface and cellular component this GO :0015106 and bicarbonate transmembrane transporter activity and molecular function this GO :0015108 and chloride transmembrane transporter activity and molecular function this GO :0015701 and bicarbonate transport and biological process this GO :0015705 and iodide transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0016887 and ATPase activity and molecular function this GO :0019869 and chloride channel inhibitor activity and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0030165 and PDZ domain binding and molecular function this GO :0030301 and cholesterol transport and biological process this GO :0030321 and transepithelial chloride transport and biological process this GO :0030324 and lung development and biological process this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0031205 and endoplasmic reticulum Sec complex and cellular component this GO :0031901 and early endosome membrane and cellular component this GO :0032870 and cellular response to hormone stimulus and biological process this GO :0034097 and response to cytokine and biological process this GO :0034707 and chloride channel complex and cellular component this GO :0042311 and vasodilation and biological process this GO :0042493 and response to drug and biological process this GO :0042626 and ATPase activity, this GO :0005224: ATP-binding and phosphorylation-dependent chloride channel activity, this GO :0005224: ATP-binding and phosphorylation-dependent chloride channel activity and also this GO :0005254: chloride channel activity and also this GO :0005260: channel-conductance-controlling ATPase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0015106: bicarbonate transmembrane transporter activity and also this GO :0015108: chloride transmembrane transporter activity and also this GO :0016887: ATPase activity and also this GO :0019869: chloride channel inhibitor activity and also this GO :0019899: enzyme binding and also this GO :0030165: PDZ domain binding and also this GO :0042626: ATPase activity, this GO :0005254: chloride channel activity, this GO :0005260: channel-conductance-controlling ATPase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0015106: bicarbonate transmembrane transporter activity, this GO :0015108: chloride transmembrane transporter activity, this GO :0016887: ATPase activity, this GO :0019869: chloride channel inhibitor activity, this GO :0019899: enzyme binding, this GO :0030165: PDZ domain binding, this GO :0042626: ATPase activity, 1 and MRP7 and TNR-CFTR, cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C |
| Identity | 1884 |
| Gene | CFTR |
| Long gene name | cystic fibrosis transmembrane conductance regulator |
| Synonyms gene | CF ABCC7 |
| Synonyms gene name | ATP-binding cassette (sub-family C, cystic fibrosis transmembrane conductance regulator, member 7) |
| Synonyms | MRP7 ABC35 TNR-CFTR dJ760C5, 1 CFTR/MRP |
| Synonyms name | ATP-binding cassette sub-family C, member 7 |
| Locus | 7q31, 2 |
| Discovery year | 1986-01-01 |
| GenBank acession | M28668 |
| Entrez gene record | 1080 |
| Pubmed identfication | 2772657 |
| RefSeq identity | NM_000492 |
| Classification | ATP-gated CFTR ATP binding cassette subfamily C , Chloride channels |
| Havana BLAST/BLAT | OTTHUMG00000023076 |
| Locus Specific Databases | Cystic Fibrosis LRG_663 |
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