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Dab1 Antibody

Dab1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDab1 Primary Polyclonal Antibody
Also known asDab1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDab1
SpecificityThis is a highly specific antibody against Dab1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dab1
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Dab1 has been shown to interact with the SH2 domains of Src, Dab2 (also designated DOC-2) is a mitogen-responsive phosphoprotein that binds the SH3 domain of Grb2, Evidence suggests that Dab1 functions downstream of Reelin in a signaling pathway involved in positioning cells in the developing brain (4), Fyn and Abl (1), Mutations in Dab1 result in widespread abnormalities in the brain, Reelin is a secreted protein thought to play a role in directing migrating neurons (3), This cytoplasmic protein is tyrosine-phosphorylated during rapid expansion of the developing nervous system, a homolog of the Drosophila Disabled protein, and it is thought to be a negative regulator of growth (5), and it is thought to interact with other proteins via a domain similar to the PTB domains of the Shc family, is an adaptor protein involved in neural development, similar to those seen in Reelin mutants (2), Dab1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym namesDAB1_HUMAN, Dab 1, Dab-1, Dab1, Disabled homolog 1, Disabled homolog 1 Drosophila, Scm, Scr, Scrambler, Yot, Yotari
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDab1
Short nameDab1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namedisabled homolog 1 (Drosophila) (Antibody to)
Alternative techniqueantibodies
Identity 49443
Gene DAB1-AS1
Long gene name DAB1 antisense RNA 1
Locus 1p32, 2
Discovery year 2013-12-03
Entrez gene record 101926890
Havana BLAST/BLAT OTTHUMG00000008286

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