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DAP12 Antibody

DAP12 Antibody size: 0.1ml 263

Price 263
Size 0.1ml
Long nameDAP12 Primary Polyclonal Antibody
Also known asDAP12 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDAP12
SpecificityThis is a highly specific antibody against DAP12
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DAP12
Tested Applications IF(IHC-P), IHC-P, FCM
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), FCM(1:20-100)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Its putative receptor, Mar 2010], Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene, Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element, This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, [provided by RefSeq, also causes PLOSL, also known as Nasu-Hakola disease, and inflammation, bone modeling, brain myelination, triggering receptor expressed on myeloid cells 2 (TREM2), This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DAP12, DNAX activation protein 12, DNAX-activation protein 12, KAR-associated protein, KARAP, Killer activating receptor associated protein, Killer-activating receptor-associated protein, PLOSL, TYOBP_HUMAN, TYRO protein tyrosine kinase binding protein, TYRO protein tyrosine kinase-binding protein, TYROBP, DAP 12
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDAP12
Short nameDAP12 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDAP12 (Antibody to)
Alternative techniqueantibodies
Identity 12449
Gene TYROBP
Long gene name TYRO protein tyrosine kinase binding protein
Synonyms gene PLOSL
Synonyms DAP12 PLO-SL KARAP
Synonyms name killer activating receptor associated protein DNAX-activation protein 12
Locus 19q13, 12
Discovery year 1998-06-25
GenBank acession AF019563
Entrez gene record 7305
Pubmed identfication 9490415 10888890
Havana BLAST/BLAT OTTHUMG00000181739
Locus Specific Databases LRG_607

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