| Long name | DAXX (Ser495) Primary Polyclonal Antibody |
| Also known as | DAXX (Ser495) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | DAXX Ser495 |
| Specificity | This phosphorylation site is homologous to that of Ser505 in Bovine, This is a highly specific antibody against DAXX Ser495 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser495 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 470-520/740 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | KLH conjugated synthetic phosphopeptide derived from human DAXX around the phosphorylation site of Ser495 |
| Gene ID number | 1616 |
| Swiss Prot | Q9UER7 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Alternative splicing results in multiple transcript variants, In the cytoplasm, In the nucleus, It interacts with a wide variety of proteins, Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli, Nov 2008], The subcellular localization and function of this protein are modulated by post-translational modifications, This protein also associates with centromeres in G2 phase, [provided by RefSeq, and transcription factor erythroblastosis virus E26 oncogene homolog 1, centromere protein C, including sumoylation, phosphorylation and polyubiquitination, such as apoptosis antigen Fas, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors, the encoded protein may function to regulate apoptosis, This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | BING2, Daxx, Death domain-associated protein 6, EAP1, ETS1-associated protein 1, Fas death domain-associated protein, hDaxx, DAP6 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | DAXX (Ser495) |
| Short name | DAXX (Ser495) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | death-domain associated protein (Ser495) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BING2 and DAP6 and EAP1, DAXX and IDBG-629026 and ENSBTAG00000016830 and 504336, DAXX and IDBG-82726 and ENSG00000204209 and 102723452, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0007257 and activation of JUN kinase activity and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008625 and extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :0016032 and viral process and biological process this GO :0016605 and PML body and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030295 and protein kinase activator activity and molecular function this GO :0030521 and androgen receptor signaling pathway and biological process this GO :0031072 and heat shock protein binding and molecular function this GO :0031396 and regulation of protein ubiquitination and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0042393 and histone binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0047485 and protein N-terminus binding and molecular function this GO :0050681 and androgen receptor binding and molecular function this GO :0070603 and SWI/SNF superfamily-type complex and cellular component this GO :0097190 and apoptotic signaling pathway and biological process this GO :1901216 and positive regulation of neuron death and biological process this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process, Daxx and IDBG-168138 and ENSMUSG00000002307 and 13163, androgen receptor binding, centromeric region and cellular component this GO :0000792 and heterochromatin and cellular component this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002039 and p53 binding and molecular function this GO :0003714 and transcription corepressor activity and molecular function this GO :0005057 and receptor signaling protein activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006334 and nucleosome assembly and biological process this GO :0006338 and chromatin remodeling and biological process this GO :0006351 and transcription, nuclei, this GO :0000281 and mitotic cytokinesis and biological process this GO :0000775 and chromosome, this GO :0002039: p53 binding, this GO :0002039: p53 binding and also this GO :0003714: transcription corepressor activity and also this GO :0005057: receptor signaling protein activity and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0019899: enzyme binding and also this GO :0019901: protein kinase binding and also this GO :0030295: protein kinase activator activity and also this GO :0031072: heat shock protein binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0042393: histone binding and also this GO :0042803: protein homodimerization activity and also this GO :0047485: protein N-terminus binding and also this GO :0050681: androgen receptor binding, this GO :0003714: transcription corepressor activity, this GO :0005057: receptor signaling protein activity, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0019899: enzyme binding, this GO :0019901: protein kinase binding, this GO :0030295: protein kinase activator activity, this GO :0031072: heat shock protein binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0042393: histone binding, this GO :0042803: protein homodimerization activity, this GO :0047485: protein N-terminus binding, this GO :0050681: androgen receptor binding, 1616, death-domain associated protein |
| Identity | 2681 |
| Gene | DAXX |
| Long gene name | death domain associated protein |
| Synonyms gene name | death-associated protein 6 |
| Synonyms | DAP6 |
| Locus | 6p21, 32 |
| Discovery year | 1998-03-25 |
| GenBank acession | AF006041 |
| Entrez gene record | 1616 |
| Pubmed identfication | 9407001 9215629 |
| Havana BLAST/BLAT | OTTHUMG00000031203 |
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