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DBC2 Antibody

DBC2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameDBC2 Primary Polyclonal Antibody
Also known asDBC2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenDBC2
SpecificityThis is a highly specific antibody against DBC2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range650-700/727
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DBC2
Gene ID number23221
Swiss ProtQ9BYZ6
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen DBC2 has been implicated as a tumor suppressor in breast and lung cancer, Studies have shown that DBC2 binds to the ubiquitin ligase scaffold Cul3, and that Cul3 regulates DBC2 protein levels by ubiquitinating DBC2 directly, leading to its degradation by the proteasome, which is part of the Rho GTPase family, DBC2 is a member of the recently identified RhoBTB family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Deleted in breast cancer 2 gene protein, KIAA0717, RHOBTB2, Rho-related BTB domain-containing protein 2, p83, DBC2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetDBC2
Short nameDBC2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDBC2 (Antibody to)
Alternative techniqueantibodies
Identity 18756
Gene RHOBTB2
Long gene name Rho related BTB domain containing 2
Synonyms gene name Rho-related BTB domain containing 2
Synonyms KIAA0717 DBC2
Locus 8p21, 3
Discovery year 2002-06-21
GenBank acession AF315385
Entrez gene record 23221
Pubmed identfication 11222756
Classification BTB domain containing Rho family GTPases
Havana BLAST/BLAT OTTHUMG00000097827

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