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DCI Antibody

DCI Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenDCI
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ICC, IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0
Notes Titration of the DCI antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis DCI antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P42126
PurityAntigen affinity
Description All classes of enoyl-CoA isomerases belong to a family of enzymes, Dodecenoyl-CoA Delta Isomerase/DCI is involved in the beta-oxidation, It does so by shifting the position of the double bonds in the acyl-CoA intermediates and converting 3-cis or trans-enoyl-CoA to 2-trans-enoyl-CoA, It plays a particularly important role in the metabolism of unsaturated fatty acids, also known as 3, and when examined with x-ray crystallography, each turn consisting of two beta-sheets and one alpha-helix, exhibit a common structural feature of the family, is an enzyme that catalyzes the conversion of cis-or trans-double bonds of fatty acids at gamma-carbon(position 3) to trans double bonds at beta-carbon(position 2), of unsaturated fatty acids with double bonds at odd-numbered carbon positions, one of the most frequently used pathways in fatty acid degradation, the N-terminal core with a spiral fold composed of four turns, the hydratase/isomerase or crotonase superfamily, 2-trans-enoyl-CoA isomerase (ECI1), Dodecenoyl-CoA Delta Isomerase
ImmunogenAn amino acid sequence from the C-terminus of human DCI (ADVQNFVSFISKDSIQKSL) was used as the immunogen for this DCI antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the DCI antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetDCI
Short nameDCI Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameDCI (Antibody to)
Alternative techniqueantibodies
Identity 2703
Gene ECI1
Long gene name enoyl-CoA delta isomerase 1
Synonyms gene DCI
Synonyms gene name dodecenoyl-Coenzyme A delta isomerase (3, 2 trans-enoyl-Coenzyme A isomerase) dodecenoyl-CoA isomerase
Synonyms name 3, 2 trans-enoyl-CoA isomerase
Locus 16p13, 3
Discovery year 1994-02-23
Entrez gene record 1632
Pubmed identfication 7829074
Havana BLAST/BLAT OTTHUMG00000128830

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